Case report: Sevelamer-associated colitis—a cause of pseudotumor formation with colon perforation and life-threatening bleeding
2023; Frontiers Media; Volume: 10; Linguagem: Inglês
10.3389/fmed.2023.1097469
ISSN2296-858X
AutoresMargareta Fištrek Prlić, Mislav Jelaković, Marko Brinar, Dora Grgić, Ivan Romić, Zlatko Marušić, Ema Ivandić, Bojan Jelaković, Ivana Vuković Lela, Željko Krznarić,
Tópico(s)Potassium and Related Disorders
ResumoChronic kidney disease (CKD) is a very common chronic non-communicable disease. Phosphate and calcium metabolism disorders are one of the most common features of CKD. Sevelamer carbonate is the most widely used non-calcium phosphate binder. Gastrointestinal (GI) injury associated with sevelamer use is a documented adverse effect but is underrecognized as a cause of gastrointestinal symptoms in patients with CKD. We report a case of a 74-year-old woman taking low-dose sevelamer with serious gastrointestinal adverse effects causing colon rupture and severe gastrointestinal bleeding.
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