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PO-03-135 LEFT ATRIAL APPENDAGE OCCLUSION VERSUS STANDARD OF CARE IN PATIENTS WITH ATRIAL FIBRILLATION AND A PRIOR THROMBO-EMBOLIC EVENT DESPITE ORAL ANTICOAGULANT THERAPY: A PROPENSITY SCORE MATCHED COMPARISON

2023; Elsevier BV; Volume: 20; Issue: 5 Linguagem: Inglês

10.1016/j.hrthm.2023.03.873

1556-3871

Moniek Maarse, David Seiffge, Errol W. Aarnink, Nicolai Fierro, Patrizio Mazzone, Alessandro Beneduce, Alessio Gasperetti, Claudio Tondo, Radek Pracon, Marcin Demkow, Kamil Zieliński, Ole De Backer, Kasper Korsholm, Jens Erik Nielsen‐Kudsk, Rodrigo Estévez‐Loureiro, Tomas Benito‐González, Luis Nombela‐Franco, Trevor Simard, Mohamad Alkhouli, David R. Holmes, Maria Rita Romeo, Sérgio Berti, Xavier Millán, Dabit Arzamendi, Venkata Alla, Christina Paitazoglou, Ingo Eitel, Xavier Freixa‐Rofastes, Solomon O. Badejoko, Rashaad Chothia, Özlem Kilic, Martin Bergmann, Daniel Spoon, Pradhum Ram, Mikhael F. El‐Chami, Luca Branca, Marianna Adamo, Kelsey Danley, Hussam Suradi, Martin J. Swaans, David J. Werring, Lucas V.A. Boersma,

Atrial Fibrillation Management and Outcomes

Patients with atrial fibrillation (AF) that suffer from ischemic stroke despite oral anticoagulant (OAC) therapy have a very high risk of recurrent stroke and better prevention strategies are needed. Left atrial appendage occlusion (LAAO) is a promising secondary prevention strategy that may provide mechanical protection. However, evidence showing effectiveness of LAAO in this population is scarce and the current international guidelines only consider LAAO in patients with a contra-indication for OAC.