Dendrimer-mediated gene delivery to boost cancer immunotherapy
2023; Future Medicine; Volume: 18; Issue: 9 Linguagem: Inglês
10.2217/nnm-2023-0124
ISSN1748-6963
AutoresMengsi Zhan, Huxiao Sun, João Rodrigues, Dzmitry Shcharbin, Mingwu Shen, Xiangyang Shi,
Tópico(s)CAR-T cell therapy research
ResumoNanomedicineAhead of Print EditorialDendrimer-mediated gene delivery to boost cancer immunotherapyMengsi Zhan, Huxiao Sun, Joao Rodrigues, Dzmitry Shcharbin, Mingwu Shen & Xiangyang ShiMengsi ZhanState Key Laboratory for Modification of Chemical Fibers & Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials & Regenerative Medicine, College of Biological Science & Medical Engineering, Donghua University, Shanghai, 201620, People's Republic of China, Huxiao SunState Key Laboratory for Modification of Chemical Fibers & Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials & Regenerative Medicine, College of Biological Science & Medical Engineering, Donghua University, Shanghai, 201620, People's Republic of China, Joao RodriguesCQM – Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus Universitário da Penteada, 9020-105, Funchal, Portugal, Dzmitry ShcharbinInstitute of Biophysics & Cell Engineering of NASB, Akademicheskaya 27, 220072, Minsk, Belarus, Mingwu ShenState Key Laboratory for Modification of Chemical Fibers & Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials & Regenerative Medicine, College of Biological Science & Medical Engineering, Donghua University, Shanghai, 201620, People's Republic of China & Xiangyang Shi *Author for correspondence: Tel.: +86 216 779 2656; E-mail Address: xshi@dhu.edu.cnhttps://orcid.org/0000-0001-6785-6645State Key Laboratory for Modification of Chemical Fibers & Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials & Regenerative Medicine, College of Biological Science & Medical Engineering, Donghua University, Shanghai, 201620, People's Republic of ChinaCQM – Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus Universitário da Penteada, 9020-105, Funchal, PortugalPublished Online:31 May 2023https://doi.org/10.2217/nnm-2023-0124AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: gene deliveryimmunotherapyPAMAM dendrimerssiRNAtumor microenvironmentReferences1. 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Adv. 6(3), eaax5032 (2020).Crossref, Medline, CAS, Google ScholarFiguresReferencesRelatedDetails Ahead of Print STAY CONNECTED Metrics Downloaded 0 times History Received 26 April 2023 Accepted 9 May 2023 Published online 31 May 2023 Information© 2023 Future Medicine LtdKeywordsgene deliveryimmunotherapyPAMAM dendrimerssiRNAtumor microenvironmentFinancial & competing interests disclosureThis work was financially supported by the National Key R&D Program (2022YFE0196900), the Science and Technology Commission of Shanghai Municipality (20520710300, 21490711500 and 20DZ2254900) and the Shanghai Education Commission through the leading talent program. J Rodrigues and X Shi also acknowledge support from the Fundação para a Ciência e a Tecnologia (FCT) with Portuguese Government funds through the CQM different Strategic Projects (CQM Base Fund – UIDB/00674/2020, Programmatic Fund – UIDP/00674/2020) and by the Agência Regional para o Desenvolvimento da Investigação Tecnologia e Inovação, respectively, through the project M1420-01-0145-FEDER-000005 – Centro de Química da Madeira – CQM+ (Madeira 14–20 Program). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.No writing assistance was utilized in the production of this manuscript.Editorial board disclosureX Shi is a member of the Nanomedicine Editorial Board. They were not involved in any editorial decisions related to the publication of this article, and all author details were blinded to the article's peer reviewers as per the journal's double-blind peer review policy.PDF download
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