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BIBTEX RIS

High Incidence of Respiratory Syncytial Virus in Children with Community-Acquired Pneumonia from a City in the Brazilian Pre-Amazon Region

2023; Multidisciplinary Digital Publishing Institute; Volume: 15; Issue: 6 Linguagem: Inglês

10.3390/v15061306

ISSN

1999-4915

Autores

Valéria Costa Fontes, Hivylla Lorrana dos Santos Ferreira, Marilene Ribeiro, Aruanã Joaquim Matheus Costa Rodrigues Pinheiro, Carlos Eduardo Campos Maramaldo, Eduardo Willian de Alencar Pereira, Luís Batista, Antônio Gilvan Teixeira Júnior, Luís Felipe Lima Lobato, F.M.F. Silva, Luís Artur Ferreira de Sousa, Washington Lima, Cláudia Lima, Suzany H. S. Soczek, Rafael Cardoso Carvalho, Mirleide Cordeiro dos Santos, Elizabeth S. Fernandes, Eduardo Martins de Sousa, Lídio Gonçãlves Lima Neto,

Tópico(s)

Pneumonia and Respiratory Infections

Resumo

Introduction: Although fewer children have been affected by the severe form of the coronavirus disease 2019 (COVID-19), community-acquired pneumonia (CAP) continues to be the leading global cause of child hospitalizations and deaths. Aim: This study investigated the incidence of respiratory syncytial virus (RSV) as well its subtypes (RSV A and B), adenovirus (ADV), rhinovirus (HRV), metapneumovirus (HMPV), coronavirus (NL63, OC43, 229E and HKU1), parainfluenza virus subtypes (PI1, PI2 and PI3), bocavirus and influenza A and B viruses (FluA and FluB) in children diagnosed with CAP during the COVID-19 pandemic. Methods: A total of 200 children with clinically confirmed CAP were initially recruited, of whom 107 had negative qPCR results for SARS-CoV-2 and were included in this study. Viral subtypes were identified using a real-time polymerase chain reaction in the nasopharyngeal swab samples. Results: Viruses were identified in 69.2% of the patients. RSV infections were the most frequently identified (65.4%), with type RSV B being the most prevalent (63.5%). In addition, HCoV 229E and HRV were detected in 6.5% and 3.7% of the patients, respectively. RSV type B was associated with severe acute respiratory infection (ARI) and a younger age (less than 24 months). Conclusions: New strategies for preventing and treating viral respiratory infections, particularly RSV infections, are necessary.

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