Artigo Acesso aberto Revisado por pares

A new tractable method for generating human alveolar macrophage-like cells in vitro to study lung inflammatory processes and diseases

2023; American Society for Microbiology; Linguagem: Inglês

10.1128/mbio.00834-23

ISSN

2161-2129

Autores

Susanta Pahari, Eusondia Arnett, Jan Simper, Abul Azad, Israel Guerrero‐Arguero, Chengjin Ye, Hao Zhang, Hong Cai, Yufeng Wang, Zhao Lai, Natalie Jarvis, Miranda Lumbreras, Diego J. Maselli, Jay I. Peters, Jordi B. Torrelles, Luis Martínez‐Sobrido, Larry S. Schlesinger,

Tópico(s)

Neonatal Respiratory Health Research

Resumo

Alveolar macrophages (AMs) are unique lung resident cells that contact airborne pathogens and environmental particulates. The contribution of human AMs (HAMs) to pulmonary diseases remains poorly understood due to the difficulty in accessing them from human donors and their rapid phenotypic change during

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