Portal de Periódicos da CAPES

Early outcomes from the Minimally Invasive Right Colectomy Anastomosis study (MIRCAST)

2023; Oxford University Press; Volume: 110; Issue: 9 Linguagem: Inglês

10.1093/bjs/znad077

1365-2168

Marcos Gómez Ruiz, Eloy Espín, Antonino Spinelli, Carmen Cagigas Fernández, Jesús Bollo, José M. Enríquez–Navascués, Tero Rautio, Mindaugas Tiskus, Eloy Espín, Antonino Spinelli, Carmen Cagigas Fernández, Jesús Bollo, José M. Enríquez–Navascués, Tero Rautio, Mindaugas Tiskus, Jorge Arredondo, Vicente Simó, Ugo Pace, Tarja Pinta, Roberto Persiani, Andrea Coratti, Paolo Pietro Bianchi, Wanda Petz, F Escobar, Vincenzo Vigorita, Nuria Truan Alonso, Esther Kreisler Moreno, Luís Miguel Jiménez, A. Valverde, Alejandro Romero, Philippe Rouanet, Α. Türler, Antonio Arroyo, Ellen Van Eetvelde, Pälvi Vento, Ángel Reina Duarte, Emre Balık, Andrea Muratore, Jim Khan, N. Rama, David Moro‐Valdezate, Ismail Gögenür, Juan Ocaña Jiménez, Goran Šantak, Éric Rullier, Irshad Shaikh, Roberto Coppola, Fernando Mendoza Santoyo, Luca Morelli, Benno Mann, Matteo Frasson, Thalia Petropoulou, Arto Turunen, Eduardo Ferrero Herrero, Jakob Lykke, Mauricio García Alonso, Javier Sánchez‐Gonzalez, Anne Mattila, Francesk Mulita, Julian Hance, Bertrand Trilling, Chiara Marafante, Markus Winny, Çağrı Büyükkasap, Imma Prós Ribas, B. Romain, Kai Leong, Orestis Ioannidis, Franco Marinello, Francesca Di Candido, Matteo Sacchi, Caterina Foppa, Lidia Cristóbal Poch, Natalia Suárez Pazos, Juan García Cardo, Gina Lladó Jordan, Camilo Palazuelos Calderón, Lucía Lavín Alconero, Julio Castillo Diego, Clàudia Codina, Carlos Placer Galán, Nerea Borda Aguizabalaga, Elisa Mäkäräinen, Karoliina Paarnio, Mirjana Komljen, Shadi Andos, Enrique Pastor, Paolo Delrio, Daniela Rega, Alberto Biondi, Laura Lorenzon, Giuseppe Giuliani, Lucia Salvischiani, Simona Borin, Uberto Fumagalli, Tamara Fernández Miguel, Raquel Sánchez Santos, Daniel Fernández Martinez, Ana Gálvez Saldaña, José Ricardo Frago Montanuy, Elena Hurtado Caballero, Paula Dujouné, María Ruíz Soriano, Beatriz De Andrés-Asenjo, Christophe Taoum, Anna Krappitz, Luzie Westphal, Luis Sánchez‐Guillén, Daniel Jacobs‐Tulleneers‐Thevissen, Dursun Buğra, Emre Özoran, Marcello Calabrò, Niclas Dohrn, Javier Díe Trill, David Jayne, Roger Gerjy, Alexis Ulrich,

Colorectal Cancer Screening and Detection

The impact of method of anastomosis and minimally invasive surgical technique on surgical and clinical outcomes after right hemicolectomy is uncertain. The aim of the MIRCAST study was to compare intracorporeal and extracorporeal anastomosis (ICA and ECA respectively), each using either a laparoscopic approach or robot-assisted surgery during right hemicolectomies for benign or malignant tumours.This was an international, multicentre, prospective, observational, monitored, non-randomized, parallel, four-cohort study (laparoscopic ECA; laparoscopic ICA; robot-assisted ECA; robot-assisted ICA). High-volume surgeons (at least 30 minimally invasive right colectomy procedures/year) from 59 hospitals across 12 European countries treated patients over a 3-year interval The primary composite endpoint was 30-day success, defined by two measures of efficacy-absence of surgical wound infection and of any major complication within the first 30 days after surgery. Secondary outcomes were: overall complications, conversion rate, duration of operation, and number of lymph nodes harvested. Propensity score analysis was used for comparison of ICA with ECA, and robot-assisted surgery with laparoscopy.Some 1320 patients were included in an intention-to-treat analysis (laparoscopic ECA, 555; laparoscopic ICA, 356; robot-assisted ECA, 88; robot-assisted ICA, 321). No differences in the co-primary endpoint at 30 days after surgery were observed between cohorts (7.2 and 7.6 per cent in ECA and ICA groups respectively; 7.8 and 6.6 per cent in laparoscopic and robot-assisted groups). Lower overall complication rates were observed after ICA, specifically less ileus, and nausea and vomiting after robot-assisted procedures.No difference in the composite outcome of surgical wound infections and severe postoperative complications was found between intracorporeal versus extracorporeal anastomosis or laparoscopy versus robot-assisted surgery.