Bio-psycho-social factors’ associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants
2023; Frontiers Media; Volume: 14; Linguagem: Inglês
10.3389/fpsyg.2023.1117732
ISSN1664-1078
AutoresMax Korbmacher, Tiril P. Gurholt, Ann‐Marie G. de Lange, Dennis van der Meer, Dani Beck, Eli Eikefjord, Arvid Lundervold, Ole A. Andreassen, Lars T. Westlye, Ivan I. Maximov,
Tópico(s)MRI in cancer diagnosis
ResumoBrain age refers to age predicted by brain features. Brain age has previously been associated with various health and disease outcomes and suggested as a potential biomarker of general health. Few previous studies have systematically assessed brain age variability derived from single and multi-shell diffusion magnetic resonance imaging data. Here, we present multivariate models of brain age derived from various diffusion approaches and how they relate to bio-psycho-social variables within the domains of sociodemographic, cognitive, life-satisfaction, as well as health and lifestyle factors in midlife to old age (
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