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Antiviral activity of silver nanoparticles against the influenza A virus

2023; Elsevier BV; Volume: 9; Issue: 2 Linguagem: Inglês

10.1016/j.jve.2023.100330

2055-6659

Krystyna Naumenko, Svіtlana Zahorodnia, Calin V. Pop, Nodari Rizun,

COVID-19 Impact on Reproduction

Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences. Silver nanoparticles (AgNPs) are considered to be an effective antimicrobial agent. This study shows that they have strong antiviral properties against the influenza A virus infection. Their absence of cytotoxicity at inhibitory concentrations demonstrates that they could be an effective antiviral agent against this virus. As AgNPs inhibit the influenza A virus replication and spread, they could also be successfully used as a post-infection virostatic agent.