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Global Prevalence and Incidence of Amyotrophic Lateral Sclerosis

2023; Lippincott Williams & Wilkins; Volume: 101; Issue: 6 Linguagem: Inglês

10.1212/wnl.0000000000207474

1526-632X

Christina Wolfson, Danielle E. Gauvin, Foluso Ishola, Maryam Oskoui,

Amyotrophic Lateral Sclerosis Research

Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disorder affecting upper and lower motor neurons. Due to its rarity and rapidly progressive nature, studying the epidemiology of ALS is challenging, and a comprehensive picture of the global burden of this disease is lacking. The objective of this systematic review was to describe the global incidence and prevalence of ALS.