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The Incidence of Multifocal Renal Cell Carcinoma in Patients Who are Candidates for Partial Nephrectomy

1995; Lippincott Williams & Wilkins; Volume: 154; Issue: 3 Linguagem: Inglês

10.1016/s0022-5347(01)66945-3

1527-3792

Matthew Whang, Kathleen O’Toole, Ronda Bixon, Jacqueline Brunetti, Edward F. Ikeguchi, Carl A. Olsson, Thor S. Sawczuk, Mitchell C. Benson,

Bladder and Urothelial Cancer Treatments

No AccessJournal of UrologyClinical Urology: Original Article1 Sep 1995The Incidence of Multifocal Renal Cell Carcinoma in Patients Who are Candidates for Partial Nephrectomy Matthew Whang, Kathleen O'Toole, Ronda Bixon, Jacqueline Brunetti, Edward Ikeguchi, Carl A. Olsson, Thor S. Sawczuk, and Mitchell C. Benson Matthew WhangMatthew Whang More articles by this author , Kathleen O'TooleKathleen O'Toole More articles by this author , Ronda BixonRonda Bixon More articles by this author , Jacqueline BrunettiJacqueline Brunetti More articles by this author , Edward IkeguchiEdward Ikeguchi More articles by this author , Carl A. OlssonCarl A. Olsson More articles by this author , Thor S. SawczukThor S. Sawczuk More articles by this author , and Mitchell C. BensonMitchell C. Benson More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)66945-3AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: A prospective study was performed to determine the incidence of multifocal renal cell carcinoma in patients who are candidates for partial nephrectomy. Materials and Methods: Preoperative imaging studies and surgical specimens in 44 patients suitable for partial nephrectomy but undergoing radical nephrectomy were prospectively reviewed. Results: Of 44 renal cell cancers 11 (25 percent) demonstrated pathological multifocality, while 10 of 11 multifocal tumors (91 percent) occurred in the face of a primary tumor 5 cm. or smaller. Tumor multifocality was independent of the size of the primary renal tumor but occurred with a slightly higher frequency in tumors of stage T3A or greater even if the primary tumor was small. Conclusions: Partial nephrectomy in patients with unilateral renal cancer should be approached with caution and should not be performed simply because it is technically feasible. References 1 : Indications for conservative surgery in certain renal tumors: a study based on the growth pattern of the clear cell carcinoma. J. Urol.1950; 64: 200. Link, Google Scholar 2 : The results of radical nephrectomy for renal cell carcinoma. J. Urol.1969; 101: 297. Link, Google Scholar 3 : Renal cell carcinoma as an incidental finding. J. Urol.1985; 134: 1094. Google Scholar 4 : Partial nephrectomy for renal cell carcinoma. In: Advances in Urology. Edited by . St. Louis: Mosby Year Book, Inc.1992: 1. chapt. 1. Google Scholar 5 : Incidental small renal tumors accompanying clinically overt renal cell carcinoma. J. Urol.1988; 140: 22. Link, Google Scholar 6 : The incidence of multicentricity in renal cell carcinoma. J. Urol.1991; 146: 1221. Link, Google Scholar 7 : Conservative surgery for renal cell carcinoma: a single-center experience with 100 patients. J. Urol.1989; 141: 835. Link, Google Scholar 8 : Information of 628 living related kidney donors at a single institution, with long-term follow-up in 472 cases. Transplant. Proc.1984; 16: 5. Google Scholar 9 : Histologic assessment and clinical prognosis of renal adenoma. J. Urol.1970; 103: 31. Link, Google Scholar 10 : A classification of renal tumors with observations on the frequency of the various types. J. Urol.1938; 39: 238. Link, Google Scholar 11 : Comparative ultrastructural study of so-called renal adenoma and carcinoma. J. Urol.1972; 108: 382. Link, Google Scholar 12 : Nephron sparing surgery in incidental versus suspected renal cell carcinoma. J. Urol.1994; 152: 39. Link, Google Scholar 13 : Renal tumors. J. Urol.1994; 152: 43. Abstract, Google Scholar 14 : Prospective analysis of multifocal renal cell carcinoma (RCC): influence of histologic pattern, grade, stage, number, volume and DNA ploidy. J. Urol.1994; 151: 314A. abstract 348. Google Scholar Departments of Urology, Pathology and Radiology, Columbia University College of Physicians and Surgeons, J. Bentley Squier Urological Clinic, Columbia-Presbyterian Medical Center, New York, New York© 1995 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byAbreu A, Berger A, Aron M, Ukimura O, Stein R, Gill I and Desai M (2012) Minimally Invasive Partial Nephrectomy for Single Versus Multiple Renal TumorsJournal of Urology, VOL. 189, NO. 2, (462-467), Online publication date: 1-Feb-2013.Simhan J, Canter D, Sterious S, Smaldone M, Tsai K, Li T, Viterbo R, Chen D, Greenberg R, Kutikov A and Uzzo R (2012) Pathological Concordance and Surgical Outcomes of Sporadic Synchronous Unilateral Multifocal Renal Masses Treated with Partial NephrectomyJournal of Urology, VOL. 189, NO. 1, (43-47), Online publication date: 1-Jan-2013.Carini M, Minervini A, Lapini A, Masieri L and Serni S (2018) Simple Enucleation for the Treatment of Renal Cell Carcinoma Between 4 and 7 cm in Greatest Dimension: Progression and Long-Term SurvivalJournal of Urology, VOL. 175, NO. 6, (2022-2026), Online publication date: 1-Jun-2006.RICHSTONE L, SCHERR D, REUTER V, SNYDER M, RABBANI F, KATTAN M and RUSSO P (2018) Multifocal Renal Cortical Tumors: Frequency, Associated Clinicopathological Features and Impact on SurvivalJournal of Urology, VOL. 171, NO. 2, (615-620), Online publication date: 1-Feb-2004.BLUTE M, THIBAULT G, LEIBOVICH B, CHEVILLE J, LOHSE C and ZINCKE H (2018) Multiple Ipsilateral Renal Tumors Discovered At Planned Nephron Sparing Surgery: Importance of Tumor Histology and Risk of Metachronous RecurrenceJournal of Urology, VOL. 170, NO. 3, (760-763), Online publication date: 1-Sep-2003.MÉJEAN A, HOPIRTEAN V, BAZIN J, LAROUSSERIE F, BENOIT H, CHRÉTIEN Y, THIOUNN N and DUFOUR B (2018) Prognostic Factors for the Survival of Patients with Papillary Renal Cell Carcinoma: Meaning of Histological Typing and MultifocalityJournal of Urology, VOL. 170, NO. 3, (764-767), Online publication date: 1-Sep-2003.SUTHERLAND S, RESNICK M, MACLENNAN G and GOLDMAN H (2018) DOES THE SIZE OF THE SURGICAL MARGIN IN PARTIAL NEPHRECTOMY FOR RENAL CELL CANCER REALLY MATTER?Journal of Urology, VOL. 167, NO. 1, (61-64), Online publication date: 1-Jan-2002.UZZO R and NOVICK A (2018) NEPHRON SPARING SURGERY FOR RENAL TUMORS: INDICATIONS, TECHNIQUES AND OUTCOMESJournal of Urology, VOL. 166, NO. 1, (6-18), Online publication date: 1-Jul-2001.Baltaci S, Orhan D, Soyupek S, Bedük Y, Tulunay Ö and Göğüs O (2018) RE: INFLUENCE OF TUMOR STAGE, SIZE, GRADE, VASCULAR INVOLVEMENT, HISTOLOGICAL CELL TYPE AND HISTOLOGICAL PATTERN ON MULTIFOCALITY OF RENAL CELL CARCINOMAJournal of Urology, VOL. 165, NO. 5, (1643-1643), Online publication date: 1-May-2001.BALTACI S, ORHAN D, SOYUPEK S, BEDÜK Y, TULUNAY Ö and GÖĞÜŞ O (2018) INFLUENCE OF TUMOR STAGE, SIZE, GRADE, VASCULAR INVOLVEMENT, HISTOLOGICAL CELL TYPE AND HISTOLOGICAL PATTERN ON MULTIFOCALITY OF RENAL CELL CARCINOMAJournal of Urology, VOL. 164, NO. 1, (36-39), Online publication date: 1-Jul-2000.GOHJI K, HARA I, GOTOH A, ETO H, MIYAKE H, SUGIYAMA T, OKADA H, ARAKAWA S and KAMIDONO S (2018) MULTIFOCAL RENAL CELL CARCINOMA IN JAPANESE PATIENTS WITH TUMORS WITH MAXIMAL DIAMETERS OF 50 MM. OR LESSJournal of Urology, VOL. 159, NO. 4, (1144-1147), Online publication date: 1-Apr-1998.WOLF J (2018) EVALUATION AND MANAGEMENT OF SOLID AND CYSTIC RENAL MASSESJournal of Urology, VOL. 159, NO. 4, (1120-1133), Online publication date: 1-Apr-1998.Campbell S, Fichtner J, Novick A, Steinbach F, Stockle M, Klein E, Filipas D, Levin H, Storkel S, Schweden F, Obuchowski N and Hale J (2018) Intraoperative Evaluation of Renal Cell Carcinoma: A Prospective Study of the Role of Ultrasonography and Histopathological Frozen SectionsJournal of Urology, VOL. 155, NO. 4, (1191-1195), Online publication date: 1-Apr-1996. Volume 154Issue 3September 1995Page: 968-971 Advertisement Copyright & Permissions© 1995 by American Urological Association, Inc.MetricsAuthor Information Matthew Whang More articles by this author Kathleen O'Toole More articles by this author Ronda Bixon More articles by this author Jacqueline Brunetti More articles by this author Edward Ikeguchi More articles by this author Carl A. Olsson More articles by this author Thor S. Sawczuk More articles by this author Mitchell C. Benson More articles by this author Expand All Advertisement PDF downloadLoading ...