Produção Nacional
Revisado por pares
Safety Assessment of the CP4 EPSPS and NPTII Proteins in Eucalyptus
2023; Landes Bioscience; Volume: 14; Issue: 1 Linguagem: Inglês
10.1080/21645698.2023.2222436
ISSN2164-5701
AutoresDror Avisar, Shelly Azulay, Lorena Bombonato, Denise Bomtempo Birche de Carvalho, Heitor Dallapicolla, Carla de Souza, Adelson Duarte Dos Santos, Tatiane Dias, Maria Paula Galan, Milton Galvão, José Mateus Wisniewski Gonsalves, Esteban Gonzales, Rodrigo Neves Graça, Sivan Livne, Reginaldo Gonçalves Máfia, Alexandre Manoeli, Mike May, Thaís Regina Drezza, Ana Cristina Pinheiro, Antônio Carlos Mota Porto, Carolina Rocha, Ariane C. Schafer, Barry W. Schafer, Edival Ângelo Valverde Zauza, William Silva,
Tópico(s)Insect Resistance and Genetics
ResumoGlyphosate herbicide treatment is essential to sustainable Eucalyptus plantation management in Brazil. Eucalyptus is highly sensitive to glyphosate, and Suzano/FuturaGene has genetically modified eucalyptus to tolerate glyphosate, with the aim of both protecting eucalyptus trees from glyphosate application damage and improving weed management. This study presents the biosafety results of the glyphosate-tolerant eucalyptus event 751K032, which expresses the selection marker neomycin phosphotransferase II (NPTII) enzyme and CP4-EPSPS, a glyphosate-tolerant variant of plant 5-enolpyruvyl-shikimate-3-phosphate synthase enzyme. The transgenic genetically modified (GM) event 751K032 behaved in the plantations like conventional non-transgenic eucalyptus clone, FGN-K, and had no effects on arthropods and soil microorganisms. The engineered NPTII and CP4 EPSPS proteins were heat-labile, readily digestible, and according to the bioinformatics analyses, unlikely to cause an allergenic or toxic reaction in humans or animals. This assessment of the biosafety of the glyphosate-tolerant eucalyptus event 751K032 concludes that it is safe to be used for wood production.
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