Voltar
Artigo Acesso aberto Revisado por pares
BIBTEX RIS

Increased oxidative stress responses in murine macrophages exposed at the air-liquid interface to third- and fourth-generation electronic nicotine delivery system (ENDS) aerosols

2023; Elsevier BV; Volume: 11; Linguagem: Inglês

10.1016/j.toxrep.2023.06.008

ISSN

2214-7500

Autores

Rakeysha Pinkston, Arthur Penn, Alexandra Noël,

Tópico(s)

Spaceflight effects on biology

Resumo

New fourth generation electronic nicotine delivery system (ENDS) devices contain high levels of nicotine salt (up to 60 mg/mL), whose cellular and molecular effects on immune cells are currently unknown. Here, we used a physiologically-relevant in vitro air-liquid interface (ALI) exposure model to assess the toxicity of distinct ENDS, a 3rd-generation electronic-cigarette (e-cig) and two 4th-generation ENDS devices (JUUL and Posh Plus).

Referência(s)