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Electrochemical Determination of N-acetylcysteine and Folic Acid in Pharmaceutical and Biological Samples Using a Modified Carbon Nanotube Paste Electrode

2014; Elsevier BV; Volume: 9; Issue: 12 Linguagem: Inglês

10.1016/s1452-3981(23)11056-x

1452-3981

Mohammad Mehdi Foroughi, Hadi Beitollahi, Somayeh Tajik, Ali Akbari, Rahman Hosseinzadeh,

Molecular Sensors and Ion Detection

2-chlorobenzoyl ferrocene, was synthesized and used to construct a modified carbon nanotube paste electrode. The electrooxidation of N-acetylcysteine at the surface of the modified electrode was studied. Under the optimized conditions, the square wave voltammetric (SWV) peak current of N- acetylcysteine increased linearly with N-acetylcysteine concentration in the ranges of 5.0 ×10-8 to 4.0 ×10-4 M. The prepared modified electrode exhibits a very good resolution between the voltammetric peaks of N-acetylcysteine and folic acid which makes it suitable for the detection of N-acetylcysteine in the presence of folic acid in real samples.