COVID-19 patients with high TNF/IFN-γ levels show hallmarks of PANoptosis, an inflammatory cell death
2023; Elsevier BV; Volume: 25; Issue: 8 Linguagem: Inglês
10.1016/j.micinf.2023.105179
ISSN1769-714X
AutoresYadira Palacios, Lucero A. Ramón‐Luing, Andy Ruíz, Alicia García-Martínez, Anahí Sánchez-Monciváis, Omar Barreto-Rodríguez, Ramcés Falfán‐Valencia, Gloria Pérez‐Rubio, Karen Medina‐Quero, Ivette Buendía-Roldán, Leslie Chávez‐Galán,
Tópico(s)Biomarkers in Disease Mechanisms
ResumoTNF and IFN-γ trigger cell damage during SARS CoV-2 infection; these cytokines can induce senescence and a cell death process called PANoptosis. This study included 138 vaccine-naïve COVID-19 patients, who were divided into four groups (Gp) according to the plasma level of TNF and IFN-γ (High [
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