Produção Nacional
Revisado por pares
Vitamin D deficiency and hyperglycemia in male rotating shift workers: A disturbed circadian rhythms influence
2023; Elsevier BV; Volume: 57; Linguagem: Inglês
10.1016/j.clnesp.2023.06.031
ISSN2405-4577
AutoresLuisa Zadra Armond de Almeida Santos, Luiz Antônio Alves de Menezes-Júnior, Sílvia Nascimento de Freitas, Fausto Aloísio Pedrosa Pimenta, George Luiz Lins Machado-Coelho, Fernando Luiz Pereira de Oliveira, Raimundo Marques do Nascimento Neto, Silvana Mara Luz Turbino Ribeiro,
Tópico(s)Climate Change and Health Impacts
ResumoShift work is related to several negative impacts on the health of workers. This study aimed to evaluate the association between vitamin D deficiency (VDD) and hyperglycemia in shift workers.This cross-sectional study included male rotating shift workers in an iron ore extraction company. Participants were classified as VDD when 25(OH)D < 20 ng/mL for a healthy population and 25(OH)D < 30 ng/mL for groups at risk for VDD. Hyperglycemia was classified when fasting glucose ≥100 mg/dL or HbA1c ≥ 5.7%. Data were compared using chi-square analysis with Cramer's V as effect size, and Bonferroni correction. Multivariate logistic regression, from a model of determination, was performed to investigate whether VDD was associated with hyperglycemia.The study evaluated 1411 workers, most workers were aged 30-39 years (53.2%), and 77.5% self-declared as black, brown, with up to complete high school (71.4%) and working alternate shifts for more than 5 years (76.1%). Regarding glucose and vitamin D, 32.0% and 29.1% of the workers had hyperglycemia and VDD, respectively. In multivariate analysis, controlled for confounding factors, workers with VDD had a 119% increased chance of hyperglycemia (OR: 2.19; IC95%: 1.56-3.08). Furthermore, vitamin D levels in distribution quintiles showed a dose-response gradient in relation to hyperglycemia, where increased vitamin D values were associated with a reduction in the occurrence of hyperglycemia.Rotating shift workers with vitamin D deficiency are more likely to have hyperglycemia.
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