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Venous thromboembolism characteristics, treatment and outcomes in young adults: findings from the Registro Informatizado de Enfermedad TromboEmbólica registry

2023; Elsevier BV; Volume: 21; Issue: 10 Linguagem: Inglês

10.1016/j.jtha.2023.06.031

1538-7933

Omri Cohen, Assaf Arie Barg, Ulrike Nowak‐Göttl, Cristina Amado-Fernández, Lucia Mazzolai, G Tiberio, Sebastian Schellong, Andris Skride, María del Valle Morales, Manuel Monréal, Gili Kenet, Manuel Monréal, Paolo Prandoni, Benjamin Brenner, Dominique Farge, Raquel Barba, Pierpaolo Di Micco, Laurent Bertoletti, Sebastian Schellong, Inna Tzoran, Abílio Reis, Marijan Bosevski, H Bounameaux, Radován Malý, Peter Verhamme, Joseph A. Caprini, My Bui, M.D. Adarraga, A. Alberich-Conesa, Jesús Alonso‐Carrillo, Cristina Amado, S. Amorós, J.I. Arcelus, Aitor Ballaz, Raquel Barba, C. Barbagelata, M. Barrón, B. Barrón‐Andrés, Á. Blanco-Molina, Enrique Ramón Botella, I. Casado, Leyre Chasco, Paula Cerdà, Juan Criado, J. del Toro, C. De Juana-Izquierdo, Pablo Demelo‐Rodríguez, A.M. Díaz-Brasero, Carmen Díaz‐Pedroche, J.A. Díaz-Peromingo, Álvaro Dubois-Silva, J.C. Escribano, F. Espósito, C. Falgá, Carmen Fernández‐Capitán, B. Fernández-Jiménez, J. Fernández-Muixí, José Luis Fernández‐Reyes, M.A. Fidalgo, Carme Font, Iria Francisco, Francisco Galeano‐Valle, M.A. García, Marta García de Herreros, F. García‐Bragado, Alberto García‐Ortega, Olga Gavín‐Sebastián, A. Gil-Díaz, Covadonga Gómez‐Cuervo, Antón Gómez-Mosquera, J. González‐Martínez, M. González-Moreno, E Grau, L. Guirado, Juan Mata, Luis Blasco, M.J. Jaras, David León Jiménez, I. Jou, M.D. Joya, B. Lacruz, S. Lainez-Justo, Antonio Lalueza, A. Latorre, Ramón Lecumberri, J.L. Lobo, M. López-De la Fuente, Luciano López‐Jiménez, Patricia López‐Miguel, Juan J. López-Núñez, Antonio López‐Ruiz, J.B. López‐Sáez, A. Lorenzo, M. Lumbierres, Olga Madridano, Ana M. Maestre, Miguel Marcos, F. Martín‐Martos, M Mellado, Edward Mena, M.I. Mercado, Jorge Moisés, M. Monreal, Arturo Muñoz Blanco, Gema Muñoz, M.V. Morales, J.A. Nieto, E. Noguera-Gras, M.J. Núñez-Fernández, Jeisson Osorio, S. Otálora, Nazaret Pacheco-Gómez, Diana Paredes-Ruíz, Pedro Parra, José María Pedrajas, C. Pérez‐Ductor, M. A. Pérez-Jacoiste, J.L. Pérez-Pérez, M.L. Peris, José Antonio Porras, J. Poyo-Molina, Ramón Puchades, A. Riera-Mestre, F. Rivera-Cívico, Alberto Rivera-Gallego, María Roca, V. Rosa, A. Rodríguez-Cobo, N. Ruiz‐Giménez, G. Salgueiro, Teresa Sancho, Vanesa Sendín, Patricia Sigüenza, S. Soler, J.M. Suriñach, G. Tiberio, Marı́a Isabel Torres, J. Trujillo-Santos, Fernando Uresandi, Esther Usandizaga, R. Valle, J.F. Varona, Lydia Vela, J. Vela, A. Villalobos, Paula Villares, Cihan Ay, Stephan Nopp, Ingrid Pabinger, Marscha M. Engelen, C. Martens, Peter Verhamme, Hugo Hyung Bok Yoo, J.D. Arguello, Ana Cristina de Albuquerque Montenegro, Juan Roa, Jana Hirmerová, Radován Malý, Sandrine Accassat, Laurent Bertoletti, A. Bura-Rivière, Judith Catella, Romain Chopard, Françis Couturaud, Olivier Espitia, Barbara Leclercq, Raphaël Le Mao, Isabelle Mahé, Farès Moustafa, L. Plaisance, Géraldine Poenou, G. Sarlon-Bartoli, Pierre Suchon, E. Versini, Sebastian Schellong, Andrei Braester, Barry E. Brenner, Gili Kenet, Inna Tzoran, Parham Sadeghipour, Manuela Basaglia, Franca Bilora, Cristiano Bortoluzzi, B. Brandolin, Maurizio Ciammaichella, Donatella Colaizzo, Antonina De Angelis, Francesco Dentali, Pierpaolo Di Micco, Elvira Grandone, Egidio Imbalzano, Simona Merla, Raffaele Pesavento, Paolo Prandoni, Paolo Scarinzi, Carmine Siniscalchi, Antonella Tufano, A. Visonà, Ngoc Vo Hong, Beniamino Zalunardo, Valdis Ģībietis, Dana Kigitoviča, Andris Skride, S. Fonseca, Manuel Maréchal, J. Meireles, Marijan Bosevski, H Bounameaux, Lucia Mazzolai, Avinash Aujayeb, Joseph A. Caprini, Ido Weinberg, H.M. Bui,

Central Venous Catheters and Hemodialysis

Background Venous thromboembolism (VTE) is rare in patients aged 21 years. Results Of 104 253 Registro Informatizado de Enfermedad TromboEmbólica patients enrolled until August 2022, 234 were adolescents and 884 were young adults. Less cases of pulmonary embolism were reported in adolescents (P < .001). Estrogen use was a common risk factor, more prevalent in adolescents and young adults (P < .001), whereas active cancer and immobilization were uncommon in both. Most patients were initially treated with low-molecular–weight heparin. VTE recurrence, major bleeding, and all-cause mortality rates were comparably low among adolescents and young adults. None of the patients aged <21 years died from VTE recurrence. Conclusion Young adults have some distinctive VTE risk factors. While VTE presentation may be similar among young adults and older patients, the outcomes of patients aged <21 years are more favorable.