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Homocysteinemia Level Determination Among Retired People in Bobo Dioulasso, Burkina Faso

2023; Science Publishing Group; Linguagem: Inglês

10.11648/j.ab.20231103.11

2329-0870

Ollo Da, Souleymane Fofana, Emmanuel Zongo, Arnaud Kouraogo, Dieudonne Sanon, Adama Traoré, Fatou Tall, Sanata Bamba, Georges Anicet Ouédraogo,

Nutrition and Health in Aging

Hyperhomocysteinemia, currently a public health problem, has been associated with the onset of critical diseases among elderly persons. Our aim in this study was to determine homocysteinemia levels in retired people. A cross sectional study was carried out among retired people in Bobo Dioulasso. Sociodemographic and clinico-biological variables were collected. Quantitative determination of total homocysteinemia in serum was carried out by a chemiluminescence microparticle immunoassay (CMIA). Three homocysteinemia levels were considered: moderate (16-30 µmol/L), intermediate (31-100 µmol/L), and severe (>100 µmol/L). Fisher's exact test was used to examine the significance of the association with a p-value of 0.05. We included a total of 71 retired people, with a median age of 64 years [minimum - maximum: 45 - 92 years], Hyperhomocysteinemia between [16-30 µmol/L [was observed in 16.90% (12/71) with a median homocysteinemia value equal to 18.71 µmol/L [minimum - maximum = 16.57 - 26.60 µmol/L]. Hyperhomocysteinemia was not significantly associated with increased blood pressure (p = 0.817), age group (p = 0.958), sex (p = 0.106), body mass index (0.053), estimated GFR (p = 0.590). A low frequency of moderate hyperhomocysteinemia was recorded in retired persons in Bobo-Dioulasso. An investigation of genetic polymorphisms associated with hyperhomocysteinemia could be considered.