Prospective Correlation of Magnetic Resonance Tumor Regression Grade With Pathologic Outcomes in Total Neoadjuvant Therapy for Rectal Adenocarcinoma
2023; Lippincott Williams & Wilkins; Volume: 41; Issue: 29 Linguagem: Inglês
10.1200/jco.22.02525
ISSN1527-7755
AutoresWilliam A. Hall, Jiahe Li, Y. Nancy You, Marc J. Gollub, Joseph R. Grajo, Mark Rosen, Greg dePrisco, Greg Yothers, Jennifer A. Dorth, Osama E. Rahma, Marcia M. Russell, Howard M. Gross, Samuel A. Jacobs, Bryan A. Faller, Sagila George, Tareq Al Baghdadi, Michael G. Haddock, Richard K. Valicenti, Theodore S. Hong, Thomas J. George,
Tópico(s)MRI in cancer diagnosis
ResumoTotal neoadjuvant therapy (TNT) is a newly established standard treatment for rectal adenocarcinoma. Current methods to communicate magnitudes of regression during TNT are subjective and imprecise. Magnetic resonance tumor regression grade (MR-TRG) is an existing, but rarely used, regression grading system. Prospective validation of MR-TRG correlation with pathologic response in patients undergoing TNT is lacking. Utility of adding diffusion-weighted imaging to MR-TRG is also unknown.
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