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Reprogramming the metabolism of oleaginous yeast for sustainably biosynthesizing the anticarcinogen precursor germacrene A

2023; Royal Society of Chemistry; Volume: 25; Issue: 20 Linguagem: Inglês

10.1039/d3gc01661g

1463-9270

Qi Liu, Ge Zhang, Liqiu Su, Pi Liu, Shiru Jia, Qinhong Wang, Zongjie Dai,

Enzyme Catalysis and Immobilization

The highest titer of the anticancer precursor sesquiterpene germacrene A was observed in oleaginous yeast using multi-layered systematic metabolic engineering strategies.