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BIBTEX RIS

Obesity, Insulin Resistance, Caries, and Periodontitis: Syndemic Framework

2023; Multidisciplinary Digital Publishing Institute; Volume: 15; Issue: 16 Linguagem: Inglês

10.3390/nu15163512

ISSN

2072-6643

Autores

Lorena Lúcia Costa Ladeira, Gustavo G. Nascimento, Fábio Renato Manzolli Leite, Silas Alves‐Costa, Janaína Maiana Abreu Barbosa, Cláudia Maria Coêlho Alves, Érika Bárbara Abreu Fonseca Thomaz, Rosângela Fernandes Lucena Batista, Cecília Cláudia Costa Ribeiro,

Tópico(s)

Nutritional Studies and Diet

Resumo

(1) Background: To investigate the grouping of obesity and insulin resistance with caries and periodontitis from a syndemic perspective through pathways of socioeconomic inequalities, smoking, alcohol, and high sugar consumption in adolescence. (2) Methods: The population-based RPS Cohort study, São Luís, Brazil, in ages 18-19 years (n = 2515) was used. The outcomes were the grouping of pbesity and Insulin Resistance Phenotype (latent variable formed by Triglycerides/HDL ratio, TyG index, and VLDL) and the Chronic Oral Disease Burden (latent variable comprising caries, bleeding on probing, probing depth ≥ 4 mm, clinical attachment level ≥ 3 mm, and visible plaque index ≥ 15%). Socioeconomic Inequalities influencing the Behavioral Risk Factors (latent variable formed by added sugar, smoking, and alcohol) were analyzed using structural equation modeling. (3) Results: Socioeconomic Inequalities were associated with the Chronic Oral Disease Burden [Standardized Coefficient (SC) = 0.222, p < 0.001]. Behavioral Risk Factors were associated with increased Chronic Oral Disease Burden (SC = 0.103; p = 0.013). Obesity was associated with the Insulin Resistance Phenotype (SC = 0.072; p < 0.001) and the Chronic Oral Disease Burden (SC = 0.066; p = 0.005). The Insulin Resistance Phenotype and the Chronic Oral Disease Burden were associated (SC = 0.053; p = 0.032). (4) Conclusion: The grouping of obesity and early events of diabetes with caries and periodontitis call for a syndemic approach in adolescence.

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