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Differences in atrial substrate localization using late gadolinium enhancement-magnetic resonance imaging, electrogram voltage, and conduction velocity: a cohort study using a consistent anatomical reference frame in patients with persistent atrial fibrillation

2023; Oxford University Press; Volume: 25; Issue: 9 Linguagem: Inglês

10.1093/europace/euad278

1532-2092

Deborah Nairn, Martin Eichenlaub, Björn Müller‐Edenborn, Taiyuan Huang, Heiko Lehrmann, Claudia Nagel, Luca Azzolin, Giorgio Luongo, R. Ventura, Barbara Rubio Forcada, Anna Vallès Colomer, Dirk Westermann, Thomas Arentz, Olaf Dössel, Axel Loewe, Amir Jadidi,

Cardiac electrophysiology and arrhythmias

Electro-anatomical voltage, conduction velocity (CV) mapping, and late gadolinium enhancement (LGE) magnetic resonance imaging (MRI) have been correlated with atrial cardiomyopathy (ACM). However, the comparability between these modalities remains unclear. This study aims to (i) compare pathological substrate extent and location between current modalities, (ii) establish spatial histograms in a cohort, (iii) develop a new estimated optimized image intensity threshold (EOIIT) for LGE-MRI identifying patients with ACM, (iv) predict rhythm outcome after pulmonary vein isolation (PVI) for persistent atrial fibrillation (AF).