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Breast Cancer in Women Under 40 Years of Age Surgical Oncology Unit of Donka National Hospital a Retrospective Cohort Study

2023; Science Publishing Group; Linguagem: Inglês

10.11648/j.crj.20231103.16

2330-8214

Malick Bah, Keita Mamady, Touré Alhassane Ismael, Cisse Kalil, Souare Mamadou Bobo, Conde Ibrahima Kalil, Traoré Bangaly,

Multiple and Secondary Primary Cancers

Objective : To describe the epidemiological, clinical, therapeutic and prognostic aspects of breast cancer in women aged 40 years and younger. Material and methods: This was are retrospective descriptive cohort of 128 months, from April 11, 2007, to December 31, 2017; including patients aged 40 years and younger who had been treated and followed up for breast cancer at the surgical oncology unit of the Donka CHU National Hospital in Conakry. Results: A total of 184 patients were enrolled in this study. The mean age was 33.5 ± 5.4 years. A family history of breast cancer was found in 16 (8.69%) patients. The presence of nodule was the most frequent symptom (91.3%). It was an infiltrating ductal carcinoma in 67.3% of patients. Stages IIIB, IV, and IIIA were the most frequent with 40.2%, 23.3% and 9.2% respectively. Mastectomy was radical in 93.9% of the cases. The associated treatments were chemotherapy (86.4%), radiotherapy (15.7%) and hormone therapy (2.7%). We recorded 79 (42.9%) deaths. Overall survival at 5 years was 31%. Conclusion: Breast cancer in young women remains serious because of its high frequency, more progressive form, and poorer prognosis compared with that of older patients.