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Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials

2023; Elsevier BV; Volume: 22; Issue: 12 Linguagem: Inglês

10.1016/s1474-4422(23)00315-0

1474-4465

Rustam Al‐Shahi Salman, Jacqueline Stephen, Jayne F. Tierney, Steff Lewis, David E. Newby, Adrian Parry‐Jones, Phil White, Stuart J. Connolly, Oscar Benavente, Dar Dowlatshahi, Charlotte Cordonnier, Catherine M. Viscoli, Kevin N. Sheth, Hooman Kamel, Roland Veltkamp, Kristin T Larsen, Jeannette Hofmeijer, Henk Kerkhoff, Floris H.B.M. Schreuder, Ashkan Shoamanesh, Catharina J.M. Klijn, H. Bart van der Worp, Didier Klug, Barbara Casolla, Laurent Puy, Morgane Coffee, Grégory Kuchcinski, Julien Labreuche, Koen M. van Nieuwenhuizen, Ale Algra, Isabelle C. Van Gelder, L. Jaap Kappelle, Gabriël J.E. Rinkel, Roger E. G. Schutgens, Pooja Khatri, Robin Conwit, Guido J. Falcone, Jordan Elm, Craig S. Anderson, Lili Song, Jeyaraj Pandian, Robert G. Hart, Mukul Sharma, Hany Aref, Wadea Tarhuni, J. Martí Fàbregas, Hans‐Christoph Diener, Matthias Endres, Robin Lemmens, Sun U. Kwon, Byung‐Chul Lee, Sebastián Ameriso, Truman J. Milling, Scott E. Kasner, Robert Mikulík, Denis Xavier, Ronny Beer, Danilo Toni, Jens Eckstein, David Seiffge, José M. Ferro, Georgios Tsivgoulis, Sanjib Kumar Sharma, Chia Wei-Liou, Stefan H. Hohnloser, Aristeidis H. Katsanos, Jackie Bosch, Jeff S. Healey, John W. Eikelboom, Alexander V. Khaw, David J. Gladstone, Aleksandra Pikula, Shelagh B. Coutts, Eric E. Smith, Kenneth Butcher, Thalia S. Field, Laura Gioia, Christian Stapf, Omid Halse, Peter Ringleb, Christian Enzinger, Igor Sibon, Joan Montaner, Valeria Caso, Peter U. Heuschmann, Gregory Y.H. Lip, Walter E. Haefeli, Stefanie Debette, Martin Dennis, Torgeir Bruun Wyller, Ole Morten Rønning, Helle Eilertsen, Hege Ihle‐Hansen, Else Charlotte Sandset, Johanna Pennlert, Eva‐Lotta Glader, Christina Kruuse, Per Wester, Maria Carlsson, Elisabeth Forfang,

Acute Ischemic Stroke Management

The safety and efficacy of oral anticoagulation for prevention of major adverse cardiovascular events in people with atrial fibrillation and spontaneous intracranial haemorrhage are uncertain. We planned to estimate the effects of starting versus avoiding oral anticoagulation in people with spontaneous intracranial haemorrhage and atrial fibrillation.