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BIBTEX RIS

Improved Antiproliferative Activity of Doxorubicin-Loaded Calcium Phosphate Nanoparticles Against Melanoma Cells

2023; Instituto de Tecnologia do Paraná (Tecpar); Volume: 66; Linguagem: Inglês

10.1590/1678-4324-2023220572

ISSN

1678-4324

Autores

Igor Barbosa Lima, Betânia Mara Alvarenga, Priscila Izabel Santos de Tótaro, Fernanda Boratto, Elaine Amaral Leite, Pedro Pires Goulart Guimarães,

Tópico(s)

Silk-based biomaterials and applications

Resumo

HIGHLIGHTS N-Dox has higher activity against A-375 cells than free doxorubicin. The formulation has higher selectivity indices than free doxorubicin. Treatment induced senescence and no colonies recovered after short-term exposure.

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