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BIBTEX RIS

Canine Pyometra: A Short Review of Current Advances

2023; Multidisciplinary Digital Publishing Institute; Volume: 13; Issue: 21 Linguagem: Inglês

10.3390/ani13213310

2076-2615

Rafael Gariglio Clark Xavier, Clarissa Helena Santana, Yasmin Gonçalves de Castro, Thayanne Gabryelle Viana de Souza, Victor Santos do Amarante, Renato L. Santos, Rodrigo Otávio Silveira Silva,

Human-Animal Interaction Studies

Pyometra, characterized by the accumulation of purulent exudate in the uterus, is the most prevalent reproductive disease in canines. While the disease often begins with mild local symptoms, it can escalate into peritonitis, sepsis, and multi-organ dysfunction, thereby posing a significant threat to life. Despite the high incidence and recognized significance of canine pyometra, gaps persist in our understanding of its epidemiology, etiology, and pathogenesis. Recent studies have, however, broadened our comprehension of this disease, shedding light on potential new infection sources, etiologies, and the application of clinical predictive biomarkers and new therapeutic protocols. This study aimed to review the current understanding of canine pyometra, with particular emphasis on the latest research concerning its etiology and epidemiology. Furthermore, it addressed key research questions and proposed directions for future investigations into various facets of canine pyometra.