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Guideline‐directed medical therapy in severe heart failure with reduced ejection fraction: An analysis from the HELP‐HF registry

2023; Elsevier BV; Volume: 26; Issue: 2 Linguagem: Inglês

10.1002/ejhf.3081

1879-0844

Daniela Tomasoni, Matteo Pagnesi, Giada Colombo, Mauro Chiarito, Davide Stolfo, Luca Baldetti, Carlo Lombardi, Marianna Adamo, Giuseppe Maggi, Riccardo M. Inciardi, Ferdinando Loiacono, Marta Maccallini, Alessandro Villaschi, Gaia Gasparini, Marco Montella, Stefano Contessi, Daniele Cocianni, Maria Perotto, Giuseppe Barone, Marco Merlo, Alberto Cappelletti, Giuseppe Rosano, Gianfranco Sinagra, Daniela Pini, Gianluigi Savarese, Marco Metra,

Cardiac pacing and defibrillation studies

Persistent symptoms despite guideline-directed medical therapy (GDMT) and poor tolerance of GDMT are hallmarks of patients with advanced heart failure (HF) with reduced ejection fraction (HFrEF). However, real-world data on GDMT use, dose, and prognostic implications are lacking.