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Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

2023; Nature Portfolio; Volume: 623; Issue: 7988 Linguagem: Inglês

10.1038/s41586-023-06717-x

ISSN

1476-4687

Autores

Tom Le Voyer, Audrey V. Parent, Xian Liu, Axel Cederholm, Adrian Gervais, Jérémie Rosain, Tina Nguyen, Malena Pérez Lorenzo, Elze Rackaityte, Darawan Rinchai, Peng Zhang, Lucy Bizien, Gonca Hancıoğlu, Pascale Ghillani‐Dalbin, Jean‐Luc Charuel, Quentin Philippot, M Guèye, Majistor Raj Luxman Maglorius Renkilaraj, Masato Ogishi, Camille Soudée, Mélanie Migaud, Flore Rozenberg, Mana Momenilandi, Quentin Riller, Luisa Imberti, Ottavia M. Delmonte, Gabriele Müller, Baerbel Keller, Julio César Orrego, William Alexander Franco Gallego, Tamar Rubin, Melike Emiroğlu, Nima Parvaneh, Daniel Eriksson, Maribel Aranda‐Guillén, David I. Berrios, Linda Vong, Constance H. Katelaris, Peter Mustillo, Johannes Raedler, Jonathan Bohlen, Jale Bengi Çelik, Camila Astudillo, Sarah Winter, Stéphanie Boisson‐Dupuis, Éric Oksenhendler, Satoshi Okada, Oana Caluseriu, Mathilde Valeria Ursini, Éric Ballot, Geoffroy Lafarge, Tomáš Freiberger, Carlos A. Arango-Franco, Romain Lévy, Alessandro Aiuti, Saleh Al‐Muhsen, Fahd Al‐Mulla, Evangelos Andreakos, Andrés A. Arias, Hagit Baris Feldman, Paul Bastard, Анастасія Бондаренко, A. Borghesi, Ahmed Aziz Bousfiha, Petter Brodin, Yenan T. Bryceson, Giorgio Casari, John Christodoulou, Roger Colobrán, Antonio Condino-Neto, Jacques Fellay, Carlos Flores, José Luis Franco, Filomeen Haerynck, Rabih Halwani, Lennart Hammarström, James R. Heath, Elena W.Y. Hsieh, Yuval Itan, Elżbieta Kaja, Kai Kisand, Cheng‐Lung Ku, Yun Ling, YL Lau, Davood Mansouri, Isabelle Meyts, Joshua D. Milner, Trine H. Mogensen, Antonio Novelli, Giuseppe Novelli, Keisuke Okamoto, Tayfun Özçelık, Rebeca Pérez de Diego, Jordi Pèrez‐Tur, David S. Perlin, Carolina Prando, Aurora Pujol, Lluís Quintana‐Murci, Laurent Rénia, Igor Resnick, Carlos Rodríguez‐Gallego, Vanessa Sancho‐Shimizu, Anna Šedivá, Mikko Seppänen, Mohammed Shahrooei, Anna Shcherbina, Pere Soler‐Palacín, Graziano Pesole, András N. Spaan, Helen C. Su, Ivan Tancevski, Ahmad Abou Tayoun, Ali Amara, Guy Gorochov, Şehime Gülsün Temel, Christian Thorball, Pierre Tiberghien, Sophie Trouillet‐Assant, Stuart E. Turvey, K. M. Furkan Uddin, Mohammed Uddin, Diederik van de Beek, Mateus Vidigal, Donald C. Vinh, Horst von Bernuth, Joost Wauters, Mayana Zatz, Shen‐Ying Zhang, Lisa F. P. Ng, Catriona McLean, Aurélien Guffroy, Joseph L. DeRisi, David Yu, Corey N. Miller, Yi Feng, Audrey Guichard, Vivien Béziat, Jacinta Bustamante, Qiang Pan‐Hammarström, Yu Zhang, Lindsey B. Rosen, Steven M. Holland, Marita Bosticardo, Heather Kenney, Riccardo Castagnoli, C Slade, Kaan Boztuğ, Nizar Mahlaoui, Sylvain Latour, Roshini S. Abraham, Vassilios Lougaris, Fabian Hauck, Anna Šedivá, Faranaz Atschekzei, Georgios Sogkas, M. Cecilia Poli, Mary Slatter, Boaz Palterer, Michael D. Keller, Alberto Pinzón‐Charry, Anna Sullivan, Luke Droney, Daniel Suan, Melanie Wong, Alisa Kane, Hannah F. Hu, S. Cindy, Hana Grombiříková, Peter Čižnár, Ilan Dalal, Nathalie Aladjidi, Anne‐Sophie Moreau, Estibaliz Lazaro, José Luis Franco, Sevgi Keleş, Marion Malphettes, Marlène Pasquet, Maria Elena Maccari, Andrea Meinhardt, Aydan İkincioğulları, Mohammad Shahrooei, Fatih Çelmeli, Patrick Frosk, Christopher C. Goodnow, Paul Gray, Alexandre Bélot, Hye Sun Kuehn, Sergio D. Rosenzweig, Makoto Miyara, Francesco Licciardi, Amélie Servettaz, Vincent Barlogis, G. Le Guenno, Vera-Maria Herrmann, Taco W. Kuijpers, Grégoire Ducoux, F. Sarrot-Reynauld, Catharina Schuetz, Charlotte Cunningham‐Rundles, Frédéric Rieux‐Laucat, Stuart G. Tangye, Cristina Sobacchi, Rainer Döffinger, Klaus Warnatz, Bodo Grimbacher, Claire Fieschi, Laureline Berteloot, Vanessa L. Bryant, Sophie Trouillet‐Assant, Helen C. Su, Bénédicte Neven, Laurent Abel, Qian Zhang, Bertrand Boisson, Aurélie Cobat, Emmanuelle Jouanguy, Olle Kämpe, Paul Bastard, Chaim M. Roifman, Nils Landegren, Luigi D. Notarangelo, Mark S. Anderson, Jean‐Laurent Casanova, Anne Puel,

Tópico(s)

Immune Response and Inflammation

Resumo

Patients with autoimmune polyendocrinopathy syndrome type 1 (APS-1) caused by autosomal recessive AIRE deficiency produce autoantibodies that neutralize type I interferons (IFNs)

Referência(s)