Effect of Intrapartum Azithromycin Versus Placebo on Neonatal Sepsis and Death: A Randomized Clinical Trial

2023; Lippincott Williams & Wilkins; Volume: 43; Issue: 4 Linguagem: Inglês

10.1097/01.aoa.0000990424.62009.02

ISSN

1536-5395

Autores

Anna Roca, Bully Camara, Joel D. Bognini, Usman Nakakana, Athasana M. Somé, Nathalie Beloum, Toussaint Rouamba, Fatoumata Sillah, Michael Danso, J. C. H. Jones, Sara Graves, Isatou Jagne Cox, Pauline Getanda, Saffiatou Darboe, Marc Christian Tahita, Ebrahim Ndure, Hien S. Franck, Sawadogo Y. Edmond, Bai Lamin Dondeh, Wilfried G. J. Nassa, Zakaria Garba, Abdoulie Bojang, Yusupha Njie, Christian Bottomley, Halidou Tinto, Umberto D’Alessandro,

Tópico(s)

Neonatal and Maternal Infections

Resumo

( JAMA . 2023;329:716–724) Approximately 40% of childhood deaths occur during the first 28 days following birth. A major cause of these deaths is sepsis. Azithromycin has been introduced as a possible solution to reduce the number of deaths occurring in infants. This study aimed to assess the use of oral azithromycin doses given to mothers during labor to reduce neonatal sepsis following delivery.

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