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The Landscape of Adaptive Evolution of a Gut Commensal Bacteria in Aging Mice

2023; Elsevier BV; Volume: 33; Issue: 23 Linguagem: Inglês

10.1016/j.cub.2023.11.021

1879-0445

Hugo C. Barreto, Ana Sousa, Isabel Gordo,

Genetics, Aging, and Longevity in Model Organisms

(Current Biology 30, 1102–1109.e1–e5; March 23, 2020) The authors wish to correct the acknowledgments that appeared in the original version of the manuscript. The original version failed to acknowledge the support by the Programa Operacional Regional do Centro, through Fundo Europeu de Desenvolvimento Regional—FEDER (CENTRO-01-0145-FEDER-030212). The authors apologize for the error. The Landscape of Adaptive Evolution of a Gut Commensal Bacteria in Aging MiceBarreto et al.Current BiologyMarch 5, 2020In BriefThe gut microbiota is thought to play a role in aging. Barreto et al. show that E. coli evolves rapidly in both old and young mice. However, in old mice, metabolic adaptations emerge more slowly and exhibit a distinct stress-related genetic signature, suggesting a more inflammatory environment in the gut of older animals. Full-Text PDF Open Archive