
Chagas disease
2023; Elsevier BV; Volume: 403; Issue: 10422 Linguagem: Inglês
10.1016/s0140-6736(23)01787-7
ISSN1474-547X
AutoresAndréa Silvestre de Sousa, Debbie Vermeij, Alberto Novaes Ramos, Alejandro O. Luquetti,
Tópico(s)Parasites and Host Interactions
ResumoChagas disease persists as a global public health problem due to the high morbidity and mortality burden. Despite the possibility of a cure and advances in transmission control, epidemiological transformations, such as urbanisation and globalisation, and the emerging importance of oral and vertical transmission mean that Chagas disease should be considered an emerging disease, with new cases occurring worldwide. Important barriers to diagnosis, treatment, and care remain, resulting in repressed numbers of reported cases, which in turn leads to inadequate public policies. The validation of new diagnostic tools and treatment options is needed, as existing tools pose serious limitations to access to health care. Integrated models of surveillance, with community and intersectional participation, embedded in the concept of One Health, are essential for control. In addition, mitigation strategies for the main social determinants of health, including difficulties imposed by migration, are important to improve access to comprehensive health care in a globalised scenario.
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