Revisão Produção Nacional Revisado por pares

Efficacy/effectiveness and safety of emicizumab prophylaxis of people with hemophilia A: a systematic review and meta-analysis

2023; Taylor & Francis; Volume: 16; Issue: 12 Linguagem: Inglês

10.1080/17474086.2023.2293096

ISSN

1747-4086

Autores

Roberto Lúcio Muniz, Ricardo Mesquita Camelo, Maiara Silva Araújo, Mariana Michel Barbosa, Augusto Afonso Guerra, Francisco de Assis Acúrcio, Juliana Álvares-Teodoro,

Tópico(s)

Hemophilia Treatment and Research

Resumo

Background Emicizumab is a monoclonal antibody approved for prophylaxis against bleeds for people with hemophilia A (PwHA). A systematic review was conducted evaluating the efficacy/effectiveness and the safety of emicizumab as prophylaxis for PwHA compared to prophylaxis with factor VIII (FVIII) or bypassing agents (BPA), respectively in patients without and with inhibitors.

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