Indocyanine green fluorescence versus blue dye, technetium-99M, and the dual-marker combination of technetium-99M + blue dye for sentinel lymph node detection in early breast cancer–meta-analysis including consistency analysis
2023; Elsevier BV; Volume: 175; Issue: 4 Linguagem: Inglês
10.1016/j.surg.2023.10.021
ISSN1532-7361
AutoresKevin P. White, Diego Sinagra, Fernando Dip, Raul J. Rosenthal, Edgar A. Mueller, Emanuele Lo Menzo, Alberto Rancati,
Tópico(s)Breast Implant and Reconstruction
ResumoAxillary sentinel lymph node biopsies are standard of care in patients with breast cancer and no clinically apparent metastases. Traditionally, technetium-99m, blue dye, or both have been used to identify sentinel lymph nodes. However, blue dyes miss up to 40% of sentinel lymph nodes, while technetium-99m use is complex, costly, and exposes patients to radiation. Over the past decade, studies have consistently found the biologically inert fluorescent indocyanine green to be 95% to 100% sensitive in detecting breast cancer sentinel lymph nodes, yet indocyanine green remains infrequently used.
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