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Population structure of Mycobacterium tuberculosis in El Oro: A first insight into Ecuador-Peru tuberculosis transmission

2024; Elsevier BV; Volume: 17; Issue: 3 Linguagem: Inglês

10.1016/j.jiph.2024.01.015

1876-035X

Bernardo Castro-Rodríguez, Kerly León-Ordóñez, Greta Franco-Sotomayor, José Manuel Benítez-Medina, Natalia Jiménez-Pizarro, Greta Esther Cardenas-Franco, Juan C. Granda, Juan Luis Aguirre-Martínez, Solón Alberto Orlando, J. Hermoso de Mendoza, Miguel Ángel García-Bereguiain,

Diagnosis and treatment of tuberculosis

Tuberculosis (TB) is a major public health concern in Ecuador and Peru, both settings of high burden of drug resistance TB. Molecular epidemiology tools are important to understand the transmission dynamics of Mycobacterium tuberculosis Complex (MTBC) and to track active transmission clusters of regional importance. This study is the first to address the transmission of TB between Peru and Ecuador through the population structure of MTBC lineages circulating in the Ecuadorian border province of "El Oro".