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Glyoxalase-based toolbox for the enantioselective synthesis of α-hydroxy carboxylic acids

2024; Royal Society of Chemistry; Volume: 22; Issue: 13 Linguagem: Inglês

10.1039/d3ob02098c

1477-0539

Mussa Yedigenov, Niyaz Amire, Aizat Abdirassil, Tomiris Mulikova, Azamat Begenov, Anniina Kiesilä, Anatoly A. Peshkov, Vsevolod A. Peshkov, Darkhan Utepbergenov,

Chemical Synthesis and Analysis

Glyoxalases DJ-1 and GlxI/II were used for the enantioselective conversion of 13 (hetero)aryl glyoxals to l - and d -α-hydroxy carboxylic acids, respectively.