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Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV

2024; American Medical Association; Volume: 9; Issue: 4 Linguagem: Inglês

10.1001/jamacardio.2023.5661

2380-6591

Michael T. Lu, Heather J. Ribaudo, Borek Foldyna, Markella V. Zanni, Thomas Mayrhofer, Júlia Karády, Jana Taron, Kathleen V. Fitch, Sara McCallum, Tricia H. Burdo, Kayla Paradis, Sandeep Hedgire, Nandini M. Meyersohn, Christopher R. deFilippi, Carlos Malvestutto, A. Sturniolo, Marissa Diggs, Sue Siminski, Gerald S. Bloomfield, Beverly Alston‐Smith, Patrice Desvigne‐Nickens, Edgar T. Overton, Judith S. Currier, Judith A. Aberg, Carl J. Fichtenbaum, Udo Hoffmann, Pamela S. Douglas, Steven Grinspoon, Carl J. Fichtenbaum, Judith A. Aberg, Eric S. Daar, Babafemi Taiwo, Susan L. Koletar, Kara W. Chew, Susan J. Little, Sonya L. Heath, Jeffrey M. Jacobson, Rajesh T. Gandhi, Gregory K. Robbins, Rachel M. Presti, Marshall J. Glesby, Annie Luetkemeyer, Pablo Tebas, Sharon A. Riddler, Michael P. Dubé, Jorge Santana‐Bagur, Beverly E. Sha, Jennifer Manne‐Goehler, Roberto C. Arduino, Charles Flexner, David W. Haas, David A. Wohl, Magdalena E. Sobieszczyk, Karen T. Tashima, Sonal S. Munsiff, Rachel Bender Ignacio, Kristen Marks, Cornelius Van Dam, Shobha Swaminathan, Thomas Campbell, Beverly Alston‐Smith, Patricia W Bandettini, Gerald S. Bloomfield, Judith S. Currier, Patrice Desvigne‐Nickens, Marissa Diggs, Pamela S. Douglas, Kathleen V. Fitch, Steven Grinspoon, Peter Kim, Michael T. Lu, Kayla Paradis, Heather J. Ribaudo, Yves Rosenberg, James Troendle, Mark Byroads, Elaine S. Gershman, Folake Lawal, Jorge Leon-Cruz, Rochelle Louis, Cheryl Lowe, Eva Moy, Triin Umbleja, Namrata Upadhyay, Stephen D. Wiviott, Kenneth W. Wood, O. Igwegbe Anthony, Radhika Barve, Fred Bone, Selina Bannoo, Annie Duffy, Carl Fletcher, M V Green, Nory Klop‐Packel, Sara McCallum, Emilia Norton, Jennifer Nowak, Maria Sanchez Grande, Sue Siminski, Eloise Walker, David Vlieg, Tricia H. Burdo, Laura Moran, Jhoanna Roa, Heather Sprenger, Bola Adedeji, Oladapo Alli, Blanca Toledo del Castillo, Joan Dragavon, K. Jack Easley, Julian Falutz, Ewelinka Grzejka, Erin Hoffman, Yuji Liao, Sara E. Looby, Dana Nohynek, Mary McCurdy Pate, James F. Rooney, Akbar Shahkolahi, Craig A. Sponseller, Kenneth C. Williams, Markella V. Zanni, Kate Borloglou, Meredith E. Clement, Allison Ross Eckard, Rebecca LeBlanc, Carlos Malvestutto, Edgar T. Overton, Karl Shaw, Virginia A. Triant, Amy Kantor, Jennifer Manne‐Goehler, Kate Starr, Ronald L. Barnett, Jane Baum, Cindy Coates, Sandra W. Cordoso, Christie Lyn Costanza, Sylvia Davila, Dushyantha Jayaweera, Teri Greenfield, Howard Gutzman, Regina Harden, Sarah Henn, MJ Humphries, Mamta K. Jain, David C. Klein, Sharon Kohrs, Javier R. Lama, Jessica Landis, Jaclyn Leone, Rita Lira, Marı́a Elena Martı́nez, Richard Novák, Karen Reese, Breno Santos, Jenese Tucker, Aimee Wilkin, T Wilson, Borek Foldyna, Júlia Karády, Thomas Mayrhofer, A. Sturniolo, Barbara Bastow, Françoise Giguel, Nada Saleh, John W. Ward, Erin Cherban, Sean S. Brummel, Janeway Granche, Carlee Moser, Pawel Paczuski, Laura Smeaton, Claire Benjamin, Tanisha Cadet, Evelynne S. Fulda, Jacqueline Murphy, Alicia Diggs, Robert S. Ettinger, Ángel Goyenechea Hernández, Janice Jarrells, Shirley Selvage, Sandeep Hedgire, Udo Hoffman, Nina M. Meyersohn, Jana Taron, Anthony Holguin, Gregory Pavlov, Scott Hammer, Martin Hirsch, JoAnn Manson, Paul M. Ridker, James H. Stein, Russell P. Tracy, James E. Udelson, Estebán Martínez, Tim Leaver, Anton Pozniak, Kathy Melbourne, Matthew J. Budoff, Chi‐Tsun Cheng, Sara F. Goldkind, Carl Grünfeld, Robert Harrington, Donald M. Lloyd‐Jones, Jennifer G. Robinson, Lynn A. Sleeper, George Sopko, Paul A. Volberding, Fassil Ketema, Karin L. Klingman, Keisha Johnson, Mark M. Mishkin, Daniella Livnat, Akin Ojumu, Alba Sierto,

Lipoproteins and Cardiovascular Health

Cardiovascular disease (CVD) is increased in people with HIV (PWH) and is characterized by premature noncalcified coronary plaque. In the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE), pitavastatin reduced major adverse cardiovascular events (MACE) by 35% over a median of 5.1 years.