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Chemical structure characterization of edible mushroom-extracted beta-glucan and its bioactivity

2024; Elsevier BV; Volume: 31; Linguagem: Inglês

10.1016/j.bcdf.2024.100411

2212-6198

Ryan Haryo Setyawan, Ardi Ardiansyah, Nissa Nurfajrin Solihat, Rizki Rabeca Elfirta, Iwan Saskiawan, Riska Surya Ningrum, Nunuk Widhyastuti, Kasirah Kasirah, Budi Saksono, Dewi Sondari, Hakiki Melanie, Bambang Nurhadi, Riksfardini Annisa Ermawar,

Phytochemistry and Bioactivity Studies

Beta-glucan has been known for its bioactivity such as for anticancer, antioxidant and antimicrobial agent. Naturally, beta-glucan is chemical structurally diverse in various beta-glucan sources such as edible mushroom. The chemical structure diversity of edible mushroom-origin beta-glucan has not yet been studied for its correlation with their bioactivity. Hence, this study observed the chemical structure and the bioactivity of beta-glucan extracted from five different edible mushrooms, which are Pleurotus ostreatus, Ganoderma lucidum, Volvariella volvacea, Agaricus bisporus, and Auricularia auricula. A. auricula contained the highest beta-glucan among the other edible mushroom (26.47 ± 3.45 g/100g). While V. volvacea beta-glucan extract possessed the highest cytotoxicity against breast cancer cells which enabled to inhibit 126.42% of cancer cells growth. It is shown that each edible mushroom has a different content of beta-glucan and bioactivity.