Produção Nacional
Revisado por pares
Dispersion patterns of SARS-CoV-2 variants Gamma, Lambda and Mu in Latin America and the Caribbean
2024; Nature Portfolio; Volume: 15; Issue: 1 Linguagem: Inglês
10.1038/s41467-024-46143-9
ISSN2041-1723
AutoresTiago Gräf, Alexander A. Martínez, Gonzalo Bello, Simon Dellicour, Philippe Lemey, Vittoria Colizza, Mattia Mazzoli, Chiara Poletto, Vanessa Leiko Oikawa Cardoso, Alexandre Freitas da Silva, Elsa Baumeister, Josefina Campos, Andrea Pontoriero, Indira Martin, Kirvina Ferguson, Draven Johnson, Songee Beckles, Kasandra Forde, Aldo Sosa, Roberto I. Meléndez, Roxana Loayza, Cinthia Avila, E. Fernández, Carol Jessica Guzman Otazo, Marilda Mendonça Siqueira, Fernando Couto Motta, Katia Corrêa de Oliveira Santos, Adriano Abbud, Mirleide Cordeiro dos Santos, Jessylene de Almeida Ferreira, Rodrigo Fasce, Jorge Fernandes, Sergio Rangel, Marcela Mercado, Dioselina Peláez, Claudio Soto-Garita, Estela Cordero-Laurent, Francisco Duarte-Martínez, Hebleen Brenes, Isaac Miguel Sánchez, Yvonne Imbert, Alfredo Bruno, Domenica Joseth de Mora Coloma, Dalia Xochitl Sandoval López, Denis Gerson Jovel Alvarado, Deny Lisset Martínez Morán, Claudia Pacheco, Linda Mendoza, Joyce Whyte-Chin, Mustapha Abdul-Kadir, Jacques Boncy, Ito Journel, Mitzi Castro Paz, Sofía Carolina Alvarado, Soany Avilez, Michelle Brown, Caludia Elena Wong Arambula, José Ernesto Ramírez–González, Alexander A. Martínez, C.M. González, Brechla Moreno Arévalo, Danilo Franco, Sandra López‐Vergès, Juan Miguel Pascale, Cynthia Vázquez, Sandra González, Nancy Rojas, Carlos Padilla, Phyllis S Pinas, Navienda Asebeh, Christine V. F. Carrington, Nikita Sahadeo, Héctor Chiparelli, Natalia Goñi, Lieska Rodríguez, Pierina D’Angelo, Fernando Couto Motta, Paola Cristina Resende, Marilda Mendonça Siqueira, Leticia Franco, Lionel Gresh, Jean-Marc Gabastou, Angel Rodríguez, Andrea Vicari, Sylvain Aldighieri, Jairo Méndez‐Rico, Juliana Almeida Leite,
Tópico(s)Virology and Viral Diseases
ResumoAbstract Latin America and Caribbean (LAC) regions were an important epicenter of the COVID-19 pandemic and SARS-CoV-2 evolution. Through the COVID-19 Genomic Surveillance Regional Network (COVIGEN), LAC countries produced an important number of genomic sequencing data that made possible an enhanced SARS-CoV-2 genomic surveillance capacity in the Americas, paving the way for characterization of emerging variants and helping to guide the public health response. In this study we analyzed approximately 300,000 SARS-CoV-2 sequences generated between February 2020 and March 2022 by multiple genomic surveillance efforts in LAC and reconstructed the diffusion patterns of the main variants of concern (VOCs) and of interest (VOIs) possibly originated in the Region. Our phylogenetic analysis revealed that the spread of variants Gamma, Lambda and Mu reflects human mobility patterns due to variations of international air passenger transportation and gradual lifting of social distance measures previously implemented in countries. Our results highlight the potential of genetic data to reconstruct viral spread and unveil preferential routes of viral migrations that are shaped by human mobility patterns.
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