Portal de Periódicos da CAPES

Artigo Produção Nacional Revisado por pares

BIBTEX RIS

Molecular hybridization: a powerful tool for multitarget drug discovery

2024; Taylor & Francis; Volume: 19; Issue: 4 Linguagem: Inglês

10.1080/17460441.2024.2322990

1746-045X

Pedro de Sena Murteira Pinheiro, Lucas Silva Franco, Tadeu L. Montagnoli, Carlos Alberto Manssour Fraga,

Cholinesterase and Neurodegenerative Diseases

Introduction The current drug discovery paradigm of 'one drug, multiple targets' has gained attention from both the academic medicinal chemistry community and the pharmaceutical industry. This is in response to the urgent need for effective agents to treat multifactorial chronic diseases. The molecular hybridization strategy is a useful tool that has been widely explored, particularly in the last two decades, for the design of multi-target drugs.