Genomic inbreeding coefficients using imputation genotypes: Assessing the effect of ancestral genotyping in Holstein-Friesian dairy cows
2024; Elsevier BV; Volume: 107; Issue: 8 Linguagem: Inglês
10.3168/jds.2024-24042
ISSN1529-9066
AutoresChristos Dadousis, Michela Ablondi, Claudio Cipolat‐Gotet, Jan-Thijs van Kaam, R. Finocchiaro, Maurizio Marusi, Martino Cassandro, Alberto Sabbioni, Andrea Summer,
Tópico(s)Reproductive Physiology in Livestock
ResumoThe objective of this study was to assess the effect of using or not using the genotypes of the parents of a cow for imputing SNPs on the estimation of genomic inbreeding coefficients of cows. Imputation (i.e., genotyped plus imputed) genotypes from 68,127 Italian Holstein dairy cows registered in the Italian National Association of Holstein, Brown, and Jersey Breeders were analyzed. Cows were genotyped with the high-density (HD) Illumina Infinium BovineHD BeadChip and GeneSeek Genomic Profiler HD-150K, and the medium-density (MD) GeneSeek Genomic Profiler 3, GeneSeek Genomic Profiler 4, GeneSeek MD, and the Labogena MD. To assess differences among estimators, genomic inbreeding coefficients were estimated with 4 PLINK v1.9 estimators (F, F
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