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Prospective, randomized, controlled trial assessing the effects of a driving pressure–limiting strategy for patients with acute respiratory distress syndrome due to community-acquired pneumonia (STAMINA trial): protocol and statistical analysis plan

2024; Volume: 36; Linguagem: Inglês

10.62675/2965-2774.20240210-en

ISSN

2965-2774

Autores

Israel Silva Maia, Fernando Azevedo Medrado, Lucas Tramujas, Bruno Martins Tomazini, Júlia Souza Oliveira, Érica Regina Ribeiro Sady, Letícia Galvão Barbante, Marina Lazzari Nicola, Rodrigo Magalhães Gurgel, Lucas Petri Damiani, Karina Leal Negrelli, Tamiris Abait Miranda, Eliana Vieira Santucci, Nanci Valeis, Ligia Nasi Laranjeira, Glauco Adrieno Westphal, Ruthy Perotto Fernandes, Cássio Luis Zandonai, Mariângela Pimentel Pincelli, Rodrigo Cruvinel Figueiredo, Cíntia Loss Sartori Bustamante, Luiz Fernando Norbin, Emerson Boschi, Rafael Lessa, Marcelo Pereira Romano, Mieko Cláudia Miura, Meton Soares de Alencar Filho, Vicente Souza-Dantas, Priscilla Alves Barreto, Mauro Esteves Hernandes, Cíntia Magalhães Carvalho Grion, Alexandre Sanches Laranjeira, Ana Luiza Mezzaroba, Marina Bahl, Ana Carolina Starke, Rodrigo Biondi, Felipe Dal‐Pizzol, Eliana Bernadete Caser, Marlus Muri Thompson, Andrea Allegrini Padial, Viviane Cordeiro Veiga, Rodrigo Thot Leite, Gustavo Araújo, Mário Guimarães, Priscilla de Aquino Martins, Fábio Holanda Lacerda, Conrado Roberto Hoffmann Filho, Lívia Maria Garcia Melro, Eduardo Pacheco, Gustavo A. Ospina‐Tascón, Juliana Carvalho Ferreira, Fabricio Jocundo Calado Freires, F.S. Machado, Alexandre Biasi Cavalcanti, Fernando G. Zampieri,

Tópico(s)

Intensive Care Unit Cognitive Disorders

Resumo

Driving pressure has been suggested to be the main driver of ventilator-induced lung injury and mortality in observational studies of acute respiratory distress syndrome. Whether a driving pressure-limiting strategy can improve clinical outcomes is unclear.

Referência(s)