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Temporal dynamics of the multi-omic response to endurance exercise training

2024; Nature Portfolio; Volume: 629; Issue: 8010 Linguagem: Inglês

10.1038/s41586-023-06877-w

1476-4687

David Amar, Nicole R. Gay, Pierre M. Jean Beltran, Dam Bae, Surendra Dasari, Courtney Dennis, Charles R. Evans, David A. Gaul, Olga Ilkayeva, Anna Ivanova, Maureen Kachman, Hasmik Keshishian, Ian R. Lanza, Ana C. Lira, Michael J. Muehlbauer, Venugopalan D. Nair, Paul Piehowski, Jessica L. Rooney, Kevin S. Smith, Cynthia L. Stowe, Bingqing Zhao, Natalie M. Clark, David Jimenez‐Morales, Maléne E. Lindholm, Gina M. Many, James Sanford, Gregory R. Smith, Nikolai G. Vetr, Tiantian Zhang, José Juan Almagro Armenteros, Julián Ávila-Pacheco, Nasim Bararpour, Yongchao Ge, Zhenxin Hou, Shruti Marwaha, David M. Presby, Archana N. Raja, Evan Savage, Alec Steep, Yifei Sun, Si Wu, Jimmy Zhen, Sue C. Bodine, Karyn A. Esser, Laurie J. Goodyear, Simon Schenk, Stephen B. Montgomery, Facundo M. Fernández, Stuart C. Sealfon, M Snyder, Joshua Adkins, Euan A. Ashley, Charles Burant, Steven A. Carr, Clary B. Clish, Gary Cutter, Robert E. Gerszten, William E. Kraus, Jun Z. Li, Michael E. Miller, K. Sreekumaran Nair, Christopher B. Newgard, Eric A. Ortlund, Weijun Qian, Russell P. Tracy, Martin J. Walsh, Matthew T. Wheeler, Karen Dalton, Trevor Hastie, Steven G. Hershman, Mihir Samdarshi, Christopher Teng, Rob Tibshirani, Elaine Cornell, Nicole Gagne, Sandy May, Brian Bouverat, Christiaan Leeuwenburgh, Ching-ju Lu, Marco Pahor, Fang‐Chi Hsu, Scott Rushing, Michael P. Walkup, Barbara J. Nicklas, W. Jack Rejeski, John P. Williams, Ashley Xia, Brent G. Albertson, Elisabeth R. Barton, Frank W. Booth, Tiziana Caputo, Michael Z. Cicha, Luís Gustavo Oliveira de Sousa, Roger P. Farrar, Andrea L. Hevener, Michael F. Hirshman, Bailey E. Jackson, Benjamin G. Ke, Kyle S. Kramer, Sarah J. Lessard, Nathan Makarewicz, Andrea G. Marshall, Pasquale Nigro, Scott K. Powers, Krithika Ramachandran, R. Scott Rector, Collyn Z-T. Richards, John P. Thyfault, Zhen Yan, Chongzhi Zang, Mary Anne S. Amper, Ali Tuğrul Balcı, Clarisa Chavez, Maria Chikina, Roxanne Chiu, Marina Gritsenko, Kristy Guevara, Joshua Hansen, Krista M. Hennig, Chia-Jui Hung, Chelsea Hutchinson-Bunch, Christopher Jin, Xueyun Liu, Kristal Maner-Smith, D.R. Mani, Nada Marjanović, Matthew Monroe, Ronald J. Moore, Samuel G. Moore, Charles C. Mundorff, Daniel Nachun, Michael Nestor, German Nudelman, Cadence Pearce, Vladislav Petyuk, Hanna Pinças, Irene Ramos, Alexander Raskind, Stas Rirak, Jeremy Robbins, Aliza B. Rubenstein, Frederique Ruf-Zamojski, Tyler J. Sagendorf, Nitish Seenarine, Tanu Soni, Karan Uppal, Sindhu Vangeti, Mital Vasoya, Alexandria Vornholt, Xuechen Yu, Elena Zaslavsky, Navid Zebarjadi, Marcas M. Bamman, Bryan C. Bergman, Daniel H. Bessesen, Thomas W. Buford, Toby L. Chambers, Paul M. Coen, Dan M. Cooper, Fadia Haddad, Kishore M. Gadde, Bret H. Goodpaster, Melissa Harris, Kim M. Huffman, Catherine M. Jankowski, Neil M. Johannsen, Wendy M. Kohrt, Bridget Lester, Edward L. Melanson, Kerrie L. Moreau, Nicolas Musi, Robert L. Newton, Shlomit Radom‐Aizik, Megan Ramaker, Tuomo Rankinen, Blake B. Rasmussen, Éric Ravussin, Irene E. Schauer, Robert S. Schwartz, Lauren M. Sparks, Anna Thalacker‐Mercer, Scott Trappe, Todd A. Trappe, Elena Volpi,

Circadian rhythm and melatonin

Regular exercise promotes whole-body health and prevents disease, but the underlying molecular mechanisms are incompletely understood