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Unraveling the Genetic Code: The Legacy of Har Gobind Khorana (January 9, 1922, to November 9, 2011)

2024; Cureus, Inc.; Linguagem: Inglês

10.7759/cureus.60048

2168-8184

Kamna Bansal,

CRISPR and Genetic Engineering

Dr. Har Gobind Khorana was an innovative chemist and Nobel laureate whose groundbreaking research laid the foundation for our understanding of the genetic code and revolutionized the field of molecular biology. Born in 1922 in Punjab, India, his journey from a small village to academic greatness showcases his intellect and determination. Despite economic challenges, Khorana pursued education, earning scholarships for studies abroad. His scientific journey began with a Ph.D. in organic chemistry from the University of Liverpool, leading to postdoctoral research in Switzerland and the UK. Notably, Khorana's work at the University of Wisconsin-Madison earned him the Nobel Prize in 1968 for deciphering the genetic code. His legacy includes synthesizing coenzyme A, deciphering the genetic code, and creating artificial genes. Honored globally, he received accolades such as the Padma Vibhushan and was commemorated on a stamp. Beyond science, Khorana's humility and mentorship left a lasting impact. His life inspires others to keep learning and discovering new things about the world, motivating them to ask questions and unravel the mysteries of the universe.