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Complications, Visual Acuity, and Refractive Error 3 Years after Secondary Intraocular Lens Implantation for Pediatric Aphakia

2024; Elsevier BV; Volume: 131; Issue: 10 Linguagem: Inglês

10.1016/j.ophtha.2024.05.011

1549-4713

Serena Wang, Michael X. Repka, Desirae R. Sutherland, Sarah R. Hatt, Elias I. Traboulsi, Scott R. Lambert, Michele Melia, Raymond T. Kraker, Jonathan M. Holmes, Susan A. Cotter, Sharon F. Freedman, David K. Wallace, Laura B. Enyedi, S. Grace Prakalapakorn, Sarah K. Jones, Denise Hug, Erin D. Stahl, Rebecca J. Dent, Lingkun Kong, Serena Wang, Bryan K. Gallerson, Amy K. Hutchinson, Phoebe D. Lenhart, Judy Brower, David G. Morrison, Scott T. Ruark, Rebecca Mets-Halgrimson, Hawke Yoon, Hantamalala Ralay Ranaivo, Aaliyah Hamidullah, Raymond G. Areaux, Jill S. Anderson, Ann M. Holleschau, Rosanne Superstein, Caroline Bélanger, Nicole Fallaha, Patrick Hamel, Maryse Thibeault, Susanna M. Tamkins, Ta Chen Chang, Hee-Jung S. Park, Anya A. Trumler, Xiaonong Liu, William F. Astle, Emi Sanders, Elias I. Traboulsi, Fatema F. Ghasia, Diana C. McOwen, Michael E. Gray, Michael B. Yang, Corey S. Bowman, Jennifer Galvin, Margaret Therriault, Heather Smith, Michele E. Whitaker, Faruk Örge, A. Paula Grigorian, Alicia M. Baird, Mitchell B. Strominger, Vicki Chen, Shelley Klein, Jacquelyn D. Kemmer, Alexandra E. Neiman, Myra N. Mendoza, Jill J. Frohwein, Don L. Bremer, Cybil Cassady, Richard P. Golden, Catherine O. Jordan, David L. Rogers, Sara A. Oravec, Tammy L. Yanovitch, Keven Lunsford, Christina Nye, Caroline Shea, SueAnn M. Stillman, Gaétan Laroche, Stephen C. Van Iderstine, Elisa Robertson, Oscar A. Cruz, Rafif Ghadban, Dawn Govreau, Scott A. Larson, Susannah Q. Longmuir, Xiaoyan Shan, Michael W. Clarke, Kate Taylor, Christine Powell, Benjamin P. Hammond, Matthew D. Gearinger, Andrea Czubinski, Dorothy Hendricks, Jing Jin, Jonathan Salvin, Alicia Fisher, Katherine A. Lee, Daniel Brooks, Bonita R. Schweinler, Nicholas A. Sala, Allyson M. Sala, Allison I. Summers, Daniel J. Karr, Lorri B. Wilson, Paula K. Rauch, Mary O’Hara, Nandini Gandhi, Tania Hashmi, Jeffrey Colburn, Eileen Dittman, Charles R. Whitfill, Amy M. Wheeler, Emily A. McCourt, Jasleen Singh, Nanastasia Welnick, Nathalie F. Azar, Joseph Baker, Patrick J. Droste, Robert J. Peters, Jan Hilbrands, Stacy L. Pineles, Marianne J. Bernardo, Edward Peterson, Charla H. Peterson, Kartik Kumar, Ephrem Melese, Robert W. Lingua, Jeff Grijalva, Earl R. Crouch, Earl R. Crouch, Gaylord Ventura, William Anninger, Shawn L. Benson, Karen A. Karp, Jordana M. Smith, Jill Brickman-Kelleher, Benjamin H. Ticho, Alexander J. Khammar, Deborah A. Clausius, Suquin Guo, Donny W. Suh, Carolyn Chamberlain, Susan Schloff, William P. Madigan, Donna Burkman, Stephen P. Christiansen, Jean E. Ramsey, Kate H. McConnell, Ilana Friedman, José Rosado, Donald P. Sauberan, Jody C. Hemberger, Patricia L. Davis, Indre Rudaitis, Robert S. Lowery, Shawn Cupit, Erick D. Bothun, Brian G. Mohney, Suzanne M. Wernimont, Rebecca A. Neilsen, Erin P. Herlihy, Francine Baran, Amy Gladstone, Justin Smith, Mei Mellott, Troy Kieser, S. Ayse Erzurum, Beth Colon, Birva Shah, Micaela Quebbemann, Roy W. Beck, Darrell S. Austin, Nicole M. Boyle, Courtney L. Conner, Danielle L. Chandler, Quayleen Donahue, Brooke P. Fimbel, Julianne L. Robinson, Amra Hercinovic, James E. Hoepner, Joseph D. Kaplon, Robert J. Henderson, B. Michele Melia, Gillaine Ortiz, Victoria C. Woodard, Kathleen M. Stutz, Desirae R. Sutherland, Rui Wu, Donald F. Everett, Marie Diener‐West, John D. Baker, Barry R. Davis, Dale L. Phelps, Stephen W. Poff, Richard Saunders, Lawrence Tychsen, Yasmin S. Bradfield, Nicole C. Foster, David A. Plager, Daniel J. Salchow, Eileen E. Birch, Ruth E. Manny, Jayne L. Silver, Katherine K. Weise, Lisa C. Verderber, Michael X. Repka, Trevano W. Dean, Raymond T. Kraker, Zhuokai Li, Kimberly G. Yen, Alejandra G. de Alba Campomanes, Marielle P. Young, Bahram Rahmani, Kathryn M. Haider, George F. Whitehead, Scott R. Lambert, Sudhi P. Kurup, Courtney L. Kraus, Susan A. Cotter, Jonathan M. Holmes,

Corneal surgery and disorders

Objective To report the cumulative incidence of complications and describe refractive error and visual acuity (VA) outcomes in children undergoing secondary intraocular lens (IOL) implantation following previous surgery for non-traumatic cataract. Design Pediatric cataract registry. Participants 80 children (108 eyes: 60 bilateral, 48 unilateral) undergoing lensectomy at <13 years of age, followed by secondary IOL implantation at median age (range) of 2.7 (0.6 to 5.0) years for bilateral and 2.1 (0.5 to 6.4) for unilateral cases. Methods Annual data collection from medical record review through 5 years following lensectomy. Main outcome measures Cumulative incidence of newly emergent complications following secondary IOL implantation; refractive error and VA by 5 years after lensectomy. Results Median (interquartile range [IQR]) follow-up following secondary IOL implantation was 2.5 years (0.8 to 3.3 years). A common complication following secondary IOL implantation was a glaucoma-related adverse event (GRAE: glaucoma or glaucoma suspect); the cumulative incidence was 17% (95% CI: 3%-29%) in bilateral and 12% (95% CI: 0%-23%) in unilateral cases. The cumulative incidence of surgery for visual axis opacification was 2% (95% CI: 0%-7%) for bilateral and 4% (95% CI: 0%-10%) for unilateral cases. Median prediction error (IQR) within 90 days of implantation was 0.88 D (-0.50 D to +3.00 D) less hyperopic than intended among 21 eyes for bilateral cases and 1.50 D (-0.25 D to +2.38 D) less among 19 unilateral cases. Median (IQR) spherical equivalent refractive error at 5 years (median 5.1 years of age) in eyes receiving a secondary IOL was +0.50 D (-2.38 D to +2.94 D) for 48 bilateral and +0.06 D (-2.25 D to +0.75 D) for 22 unilateral cases. Median (IQR) monocular VA at 5 years was 20/63 (20/50-20/100) for bilateral (n=42) and 20/400 (20/160-20/800) for unilateral (n=33) cases. Conclusions Eyes with secondary IOL implantation have an ongoing risk of new glaucoma-related adverse events. Five years after lensectomy (approximately 2.5 years after secondary IOL implantation), average refractive error was less hyperopic than desired given the anticipated further myopic shift before refraction stabilizes. To report the cumulative incidence of complications and describe refractive error and visual acuity (VA) outcomes in children undergoing secondary intraocular lens (IOL) implantation following previous surgery for non-traumatic cataract. Pediatric cataract registry. 80 children (108 eyes: 60 bilateral, 48 unilateral) undergoing lensectomy at <13 years of age, followed by secondary IOL implantation at median age (range) of 2.7 (0.6 to 5.0) years for bilateral and 2.1 (0.5 to 6.4) for unilateral cases. Annual data collection from medical record review through 5 years following lensectomy. Cumulative incidence of newly emergent complications following secondary IOL implantation; refractive error and VA by 5 years after lensectomy. Median (interquartile range [IQR]) follow-up following secondary IOL implantation was 2.5 years (0.8 to 3.3 years). A common complication following secondary IOL implantation was a glaucoma-related adverse event (GRAE: glaucoma or glaucoma suspect); the cumulative incidence was 17% (95% CI: 3%-29%) in bilateral and 12% (95% CI: 0%-23%) in unilateral cases. The cumulative incidence of surgery for visual axis opacification was 2% (95% CI: 0%-7%) for bilateral and 4% (95% CI: 0%-10%) for unilateral cases. Median prediction error (IQR) within 90 days of implantation was 0.88 D (-0.50 D to +3.00 D) less hyperopic than intended among 21 eyes for bilateral cases and 1.50 D (-0.25 D to +2.38 D) less among 19 unilateral cases. Median (IQR) spherical equivalent refractive error at 5 years (median 5.1 years of age) in eyes receiving a secondary IOL was +0.50 D (-2.38 D to +2.94 D) for 48 bilateral and +0.06 D (-2.25 D to +0.75 D) for 22 unilateral cases. Median (IQR) monocular VA at 5 years was 20/63 (20/50-20/100) for bilateral (n=42) and 20/400 (20/160-20/800) for unilateral (n=33) cases. Eyes with secondary IOL implantation have an ongoing risk of new glaucoma-related adverse events. Five years after lensectomy (approximately 2.5 years after secondary IOL implantation), average refractive error was less hyperopic than desired given the anticipated further myopic shift before refraction stabilizes.