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Targeting enhanced cell death represents a potential therapeutic strategy for VEXAS syndrome

2024; Oxford University Press; Volume: 8; Issue: 2 Linguagem: Inglês

10.1093/rap/rkae065

2514-1775

Soichiro Adachi, Yohei Kirino, Kana Higashitani, Lisa Hirahara, Ayaka Maeda, Nobuyuki Horita, Kaoru Takase-Minegishi, Ryusuke Yoshimi, Hideaki Nakajima,

Vascular Anomalies and Treatments

To unravel the mechanisms underlying cell death in the vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome using peripheral blood samples and to assess the clinical value of this knowledge.