Voltar
Artigo Revisado por pares
BIBTEX RIS

Elevated senescence-associated secretory phenotype index in late-life bipolar disorder

2024; Elsevier BV; Volume: 360; Linguagem: Inglês

10.1016/j.jad.2024.05.071

ISSN

1573-2517

Autores

Tselot Tessema, Breno S. Diniz, Érica Leandro Marciano Vieira, Ana Paula Mendes‐Silva, Aristotle N. Voineskos, Ariel Gildengers, M. Ishrat Husain, Abigail Ortiz, Daniel M. Blumberger, Tarek K. Rajji, Benoit H. Mulsant,

Tópico(s)

Genetics and Neurodevelopmental Disorders

Resumo

The senescence-associated secretory phenotype (SASP) is a biomarker index based on the profile of 22 blood proteins associated with cellular senescence. The SASP index has not been assessed in older patients with bipolar disorder (BD). We hypothesized that older adults with BD will have elevated cellular senescence burden as measured by the SASP index.

Referência(s)