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Revisão Acesso aberto Produção Nacional Revisado por pares

BIBTEX RIS

Coastal natural products: a review applied to antimycobacterial activity

2024; Taylor & Francis; Linguagem: Inglês

10.1080/14786419.2024.2361333

1478-6427

Rodolfo Moreira Baptista, Marcos Alaniz Rodrigues, Fábio Roselet, César Serra Bonifácio Costa, Pedro Eduardo Almeida da Silva, Daniela Fernandes Ramos,

Carbohydrate Chemistry and Synthesis

Despite the many advances in drug research, natural products are still being explored as a promising source for discovering new bioactive compounds to treat global diseases such as tuberculosis. However, there is a lack of studies and information about coastal natural products, which thrive in the transitional environment between two different ecosystems and produce unique secondary metabolites. Mangroves, estuaries, and mudflats make up areas for coastal species and have shown promising results in antituberculosis research, some of them are present in hotspot areas. This review focuses on research conducted in coastal environments and explores the reasons why these natural products tend to outperform non-coastal ones against the causative agent of tuberculosis, Mycobacterium tuberculosis.