Morpholine, Piperazine, and Piperidine Derivatives as Antidiabetic Agents
2024; Multidisciplinary Digital Publishing Institute; Volume: 29; Issue: 13 Linguagem: Inglês
10.3390/molecules29133043
ISSN1433-1373
AutoresDarya Zolotareva, Alexey Zazybin, Anuar Dauletbakov, Yelizaveta Belyankova, Beatriz Giner, Saniya Tursynbek, Т. М. Сейлханов, Anel Kairullinova,
Tópico(s)Enzyme function and inhibition
ResumoDiabetes mellitus is a severe endocrine disease that affects more and more people every year. Modern medical chemistry sets itself the task of finding effective and safe drugs against diabetes. This review provides an overview of potential antidiabetic drugs based on three heterocyclic compounds, namely morpholine, piperazine, and piperidine. Studies have shown that compounds containing their moieties can be quite effective in vitro and in vivo for the treatment of diabetes and its consequences.
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