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BIBTEX RIS

Oxygenated versus non‐oxygenated flush out during deceased donor liver procurement: The first proof‐of‐concept study in humans

2024; Wiley; Volume: 48; Issue: 11 Linguagem: Inglês

10.1111/aor.14815

1525-1594

Eduardo de Souza Martins Fernandes, R Correa, Rodrigo Lopes Leite Furtado, Isabel M.A. Brüggenwirth, Cindy Yang, Felipe Pedreira Tavares de Mello, R Andrade, Leandro Moreira Savattone Pimentel, Camila Liberato Girão, Camilla César, Munique Ana Pimentel Siqueira, Eduardo Pinho Braga, A. C. Carvalho, Robert J. Porte, Eliete Bouskela,

Organ Donation and Transplantation

Liver transplantation is used for treating end-stage liver disease, fulminant hepatitis, and oncological malignancies and organ shortage is a major limiting factor worldwide. The use of grafts based on extended donor criteria have become internationally accepted. Oxygenated machine perfusion technologies are the most recent advances in organ transplantation; however, it is only applied after a period of cold ischemia. Due to its high cost, we aimed to use a novel device, OxyFlush®, based on oxygenation of the preservation solution, applied during liver procurement targeting the maintenance of ATP during static cold storage (SCS).