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Sex ratio and age of onset in AQP4 antibody-associated NMOSD: a review and meta-analysis

2024; Springer Science+Business Media; Volume: 271; Issue: 8 Linguagem: Inglês

10.1007/s00415-024-12452-8

1432-1459

Simon Arnett, Sin Hong Chew, Unnah Leitner, Jyh Yung Hor, Friedemann Paul, Michael R. Yeaman, Michael Levy, Brian G. Weinshenker, Brenda Banwell, Kazuo Fujihara, Hesham Abboud, Irena Dujmović, Georgina Arrambide, Veronika E. Neubrand, Chao Quan, Esther Melamed, Jacqueline Palace, Jing Sun, Nasrin Asgari, Simon Broadley, Hesham Abboud, Orhan Aktaş, Raed Alroughani, Ayşe Altıntaş, Metha Apiwattannakul, Georgina Arrambide, Jagannadha Avasarala, Brenda Banwell, Terrence F. Blaschke, James D. Bowen, Edgar Carnero Contentti, Tanuja Chitnis, de Sèze, Guillermo Delgado‐García, Irena Dujmović, José Flores‐Rivera, Kazuo Fujihara, Lorna Galleguillos, Benjamin Greenberg, May Han, Joachim Havla, Kerstin Hellwig, Jyh Yung Hor, Sven Jarius, Jorge Andres Jimenez, Najib Kissani, Ingo Kleiter, Marco Lana-Peixoto, Maria Isabel Leite, Michael Levy, Sara Mariotto, Maureen A. Mealy, Veronika E. Neubrand, Celia Oreja‐Guevara, Lekha Pandit, Sarah M. Planchon, Anne‐Katrin Pröbstel, Peiqing Qian, Chao Quan, Pavle Repovic, Claire Riley, Marius Ringelstein, Juan Ignacio Rojas, Dalia Rotstein, Klemens Ruprecht, María José Sá, Albert Saiz, Sara Salama, Sasitorn Siritho, Aksel Sıva, Terry J. Smith, Elias S. Sotirchos, Ibis Soto de Castillo, Silvia Tenembaum, Pablo Villoslada, Barbara Willekens, Dean M. Wingerchuk, Bassem Yamout, Michael R. Yeaman,

Peripheral Neuropathies and Disorders

Aquaporin-4 (AQP4) antibody-associated neuromyelitis optica spectrum disorder (NMOSD) is an antibody-mediated inflammatory disease of the central nervous system. We have undertaken a systematic review and meta-analysis to ascertain the sex ratio and mean age of onset for AQP4 antibody associated NMOSD. We have also explored factors that impact on these demographic data.