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Interleukin (IL)-1/IL-6-Inhibitor–Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses

2024; Elsevier BV; Volume: 12; Issue: 11 Linguagem: Inglês

10.1016/j.jaip.2024.07.002

2213-2201

Vivian E Saper, Lü Tian, Ruud H J Verstegen, C. Conrad, Michal Cidon, Rachel K. Hopper, Christin S. Kuo, Kazutoyo Osoegawa, Kevin Baszis, Catherine April Bingham, Ian Ferguson, Timothy Hahn, AnnaCarin Horne, E.A. Isupova, Jordan T. Jones, Özgür Kasapçopur, Marisa S. Klein‐Gitelman, М. М. Костик, Seza Özen, Omkar Phadke, Sampath Prahalad, Rachel L. Randell, Seher Şener, Cory Stingl, Rabheh Abdul‐Aziz, Shoghik Akoghlanian, Dalila Al Julandani, M. Alvarez, Brigitte Bader‐Meunier, Erin Balay‐Dustrude, Imelda Balboni, Sarah K. Baxter, Roberta Berard, Sagar Bhattad, Roxana Bolaria, Alexis Boneparth, Elaine Cassidy, Dominic O. Co, Kathleen P Collins, Paul Dancey, Aileen M Dickinson, Barbara S Edelheit, Graciela Espada, Elaine R Flanagan, Lisa F. Imundo, Ankur Kumar Jindal, Hyoun‐Ah Kim, Günter Klaus, Carol L. Lake, William Blaine Lapin, Erica Lawson, Itay Marmor, Joy Mombourquette, Benson Ogunjimi, Rebecca Olveda, Michael J. Ombrello, Karen Onel, Catherine H. Poholek, Athimalaipet V Ramanan, Angelo Ravelli, Adam Reinhardt, Amanda D Robinson, Kelly Rouster‐Stevens, Nadine Saad, Rayfel Schneider, Velma Selmanovic, Irmina Sefic Pasic, Susan Shenoi, Natalie R. Shilo, Jennifer B. Soep, Asmiti Sura, Sarah F. Taber, Melissa Tesher, Jessica Tibaldi, Kathryn S. Torok, Cathy Mei Tsin, Natalia Vasquez‐Canizares, D. Sofia Villacis-Nunez, Emily E. Way, Benjamin Whitehead, Lawrence Zemel, Surbhi Sharma, Marcelo Fernández-Viña, Elizabeth Mellins,

Urticaria and Related Conditions

After introducing IL-1/IL-6 inhibitors, some patients with Still and Still-like disease developed unusual, often fatal, pulmonary disease. This complication was associated with scoring as DReSS (drug reaction with eosinophilia and systemic symptoms) implicating these inhibitors, although DReSS can be difficult to recognize in the setting of systemic inflammatory disease.